Meibomian Gland Dysfunction: Endocrine Aspects
October 2011
in “
ISRN Ophthalmology
”
Studysummary This study found that increased serum testosterone and dehydroepiandrosterone sulphate levels may serve as diagnostic markers for seborrheic meibomian gland dysfunction in both genders.
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The study investigated the endocrine aspects of seborrheic Meibomian Gland Dysfunction (MGD) by comparing hormone levels in 50 patients with 50 controls. It found that patients with seborrheic MGD had significantly higher serum levels of testosterone and dehydroepiandrosterone sulphate (DHEA-S) in both genders, suggesting these hormones could serve as diagnostic markers. In females, significant differences were also observed in thyroid-stimulating hormone (TSH) and prolactin levels. No significant differences were found in other hormones such as T3, T4, FSH, LH, 17-OH-Prog, estradiol, cortisol, and thyroglobulin. The study highlighted the potential role of androgens in the pathogenesis of seborrheic MGD.
