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PX-12 may help treat psoriasis by blocking inflammation and cell death.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.

Androgenetic alopecia is common in South-West Nigeria, affecting more men than women, with stress worsening the condition.

Hair loss in adults is linked to heart disease risk factors like unhealthy blood fats, lack of exercise, and alcohol use. It's also slightly more common in people with metabolic syndrome. As people age, hair loss gets worse. In men, severe hair loss is tied to high blood pressure and a larger waist. In women, it's tied to higher body weight. People with hair loss should be checked for unhealthy blood fats and advised to avoid alcohol and inactivity.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.

The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.

Darkened knuckles can be an early sign of insulin resistance.

Testosterone injections can cause skin darkening and thickening.

A Nigerian baby with neonatal lupus got better with treatment by 6 months.

Stopping birth control pills may have triggered a manic episode in a woman with HAIR-AN syndrome.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

Acanthosis nigricans in teenage girls with PCOS is a sign of obesity, not insulin resistance or glucose intolerance.

A Nigerian teenager was diagnosed with neuropsychiatric lupus, showing various severe symptoms and abnormal lab results.

The case shows skin changes can indicate deeper health issues like insulin resistance, which are challenging to manage.

A patient with HAIR-AN syndrome, PCOS, and Hashimoto's thyroiditis improved with early diagnosis and treatment to prevent serious health problems.

The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.

Most patients improved with oral contraceptives, but some needed additional treatment.

A significant number of Nigerian women struggling with infertility have Polycystic Ovary Syndrome, with the exact percentage varying based on the diagnostic criteria used.

Higher testosterone levels in Nigerian women with PCOS are linked to glucose disorders like diabetes.

SLE is more common among Nigerians than previously thought, especially in women, requiring early treatment.

Certain gene variations are not a major cause of male infertility in Nigerian men.