Mania in Hyperandrogenism, Insulin Resistance, and Acanthosis Nigricans Syndrome

    February 2002 in “ ˜The œAmerican journal of psychiatry ”
    Yiu-Chung Chan, Mary Beth Hankins, Bevila John-Daniel
    TLDR Stopping birth control pills may have triggered a manic episode in a woman with HAIR-AN syndrome.
    The document from 2002 reported a case of a 19-year-old woman with Hyperandrogenism, Insulin Resistance, and Acanthosis Nigricans (HAIR-AN) syndrome who experienced her first manic episode after discontinuing her birth control pills. The patient's symptoms included elevated mood, lessened need for sleep, racing thoughts, pressured speech, and grandiose delusions. Her physical examination revealed a male pattern of hair growth on her face and hyperpigmented skin on the neck. Endocrinological tests confirmed the diagnosis of HAIR-AN syndrome with elevated insulin and testosterone levels. The patient's manic symptoms were successfully treated with lithium, divalproex sodium, and quetiapine. The document suggested that this might be the first documented case of mania in a patient with HAIR-AN syndrome, and the manic symptoms emerged 2 months after she stopped treatment with oral contraceptives. However, the authors noted that further study was needed to confirm the association.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 9 results

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  6 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Balding without a family history

      in Chat  6 upvotes 1 week ago
      The user is experiencing hair loss without a family history and suspects stress or telogen effluvium (TE) as the cause, despite using finasteride without results. Others suggest stress, vitamin deficiencies, or other conditions could be factors, and some mention that balding can occur without a family history.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 1 year ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Dutasteride is amazing even for women with FAGA!

      in Female  151 upvotes 3 months ago
      Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

    Related Research

    1 / 1 results