April 2024 in “Journal of psychiatric research” This study observed that short-term administration of finasteride in male Wistar rats induced anxiety-like and depression-like behaviors, impaired spatial learning and memory, and reduced synaptic plasticity in the hippocampus, with a trend of increased corticosterone levels noted.
January 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that patients with trichodynia associated with androgenetic alopecia had significantly higher levels of substance P in both tissue and serum compared to healthy controls, suggesting a potential role for this neurotransmitter in the condition's pathogenesis.
In this study, significant associations were observed between specific genetic polymorphisms in BDNF and CRH-R1 and the occurrence of vitiligo, along with differing serum levels of neurotransmitters between vitiligo patients and healthy controls.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the authors explored the multifaceted connection between stress and stress-induced telogen effluvium, emphasizing how elevated cortisol levels and impaired microcirculation contribute to hair loss, along with potential interventions, including both medicinal and non-medicinal strategies like relaxation techniques and gentle care rituals.
April 2023 in “Journal of Investigative Dermatology” This review evaluates controlled studies on Platelet-Rich Plasma for androgenetic alopecia treatment, reporting positive effects on hair growth and density but highlighting the need for standardized protocols.
November 2024 in “Journal of Investigative Dermatology” Skin and hair cells release serotonin and histamine naturally, which could help improve skin health.
September 2023 in “F&S reports” This review examines theories linking PCOS with psychiatric disorders, highlighting dietary interventions like probiotics and nutrients as possible improvements, but reports no new clinical findings and calls for more research.
11 citations
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November 2022 in “Food and Chemical Toxicology” This study found that microalgal extract from Botryococcus terribilis exhibited antidepressant-like effects in mice by regulating neuroinflammation and modulating neurotransmitter systems.
19 citations
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March 2022 in “International Journal of Environmental Research and Public Health” This review covers the neuroendocrine aspects of polycystic ovary syndrome, focusing on hormones and neurotransmitters like GnRH and kisspeptin, but does not report new clinical findings.
11 citations
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January 2016 in “Bipolar Disorder” This article reviews the uses, mechanisms, and side effects of valproate in treating bipolar disorder, noting its first-line status for several manic conditions but also highlighting serious risks such as fetal abnormalities.
1 citations
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June 2023 in “Reproduction” This review discusses the role of microglia in mediating prenatal androgen effects on the female brain, potentially contributing to PCOS development and neuroendocrine dysfunctions, but reports no new results.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study discusses how stress can lead to telogen effluvium, a form of hair loss, by triggering hormonal imbalances and affecting microcirculation and hair follicle homeostasis. It highlights both medicinal and non-medicinal interventions, such as relaxation techniques and gentle care rituals, as potential treatment strategies.
October 2022 in “Biomolecules” This study found that in male rats, chronic finasteride treatment reduced allopregnanolone levels, which, upon drug withdrawal, correlated with increased pro-inflammatory cytokines and altered neurotransmitter levels.
September 2025 in “Frontiers in Pharmacology” This study suggests that P. orientalis leaf-derived EVs could offer anxiolytic, antidepressant, and sleep-inducing benefits by affecting neurotransmitter levels and reducing inflammation, particularly when administered intranasally.
August 2021 in “Research Square (Research Square)” This study found that ferulic acid significantly reduced seizure susceptibility and depression-like behaviors in a mouse model of catamenial epilepsy, likely by restoring hormone levels and neurotransmitter activity.
August 2022 in “Metabolic Brain Disease” In this study with a mouse model of catamenial epilepsy, ferulic acid may effectively reduce seizure susceptibility and depression-like behavior by influencing hormone levels and neurotransmitter activity.
17 citations
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April 2006 in “Brain Research” This study found that stimulation with certain neurotransmitters and hormones suggests the involvement of 5α-reduced neurosteroids in glial cell differentiation in rat C6 glioma cells.
27 citations
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October 2018 in “Saudi Journal of Biological Sciences” This study found that curcumin administration improved cognitive and anxiety-related behaviors and neurochemical levels in HgCl2 exposed mice pups, suggesting protective effects against heavy metal-induced neurotoxicity.
7 citations
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January 2020 in “Journal of King Saud University - Science” This study found that celery supplementation improved cognition and behavioral disorders in LPS-exposed mouse offspring by increasing levels of dopamine, acetylcholinesterase, and serotonin in the forebrain.
393 citations
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November 2000 in “Archives of General Psychiatry” This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.
In this study, rat vibrissa follicles transplanted into mice demonstrated survival, partial sympathetic nerve reinnervation, and increased norepinephrine levels 37 days post-implantation, suggesting potential for hair growth despite not returning to normal nerve function.
142 citations
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January 2019 in “Frontiers in Neuroendocrinology” This review summarizes proposed pathophysiological mechanisms of postpartum depression, highlighting neuroendocrine and neurobiological changes, but reports no new findings and calls for integrated understanding of the disorder.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” This review discusses the complex relationship between stress and various skin conditions, highlighting the role of the skin in the stress response and the brain-skin communication pathways, but reports no new research findings.
1 citations
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February 2010 in “Proceedings of SPIE” This study suggests that low level laser therapy may promote hair cell regeneration in rat cochlear explants following gentamicin-induced damage.
June 2011 in “CRC Press eBooks” Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
38 citations
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January 2023 in “International Journal of Medical Sciences” This review discusses the potential of repeated low-level red-light therapy to inhibit myopia progression through metabolic effects, highlighting its molecular and cellular impact, but reports no new clinical results.
This study found that pediatric alopecia areata patients had significantly lower serum BDNF levels compared to healthy controls, which were associated with greater alopecia severity, higher depressive symptoms, and poorer quality of life.
December 2025 in “Frontiers in Endocrinology” This study found that elevated CgA levels in PCOS are associated with obesity, insulin resistance, and low-grade inflammation, suggesting CgA may be a novel biomarker for metabolic risk stratification in PCOS.
61 citations
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January 2008 in “Biological & Pharmaceutical Bulletin” In this study, finasteride dose-dependently inhibited stress-induced increases in allopregnanolone in rats, while enhancing 20alpha-reduction of progesterone without affecting 3alpha-dihydroprogesterone or 11-deoxycorticosterone levels.
59 citations
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November 2018 in “Psychoneuroendocrinology” This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.