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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

Synthetic polypeptides in cosmetics may help with anti-aging, but their effectiveness on real skin is uncertain.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Using a special skin cream with gabapentin helped reduce symptoms of a certain scalp condition but didn't change nerve fibers or skin chemicals.

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

Stress hormones and autoimmune reactions can cause hair loss.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

Researchers found genes that may explain why some pigs grow winter hair, which could help breed cold-resistant pigs.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

Nerves and chemicals in the body can affect hair growth and loss.

The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Certain drugs can cause early hair growth in mice by affecting the nerves.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.

Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.