The Use of Synthetic Polypeptides in Cosmetics

    December 2010 in “ Copernican Letters
    Beata Łubkowska, Beata Grobelna, Zbigniew Maćkiewicz
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    TLDR Synthetic polypeptides in cosmetics may help with anti-aging, but their effectiveness on real skin is uncertain.
    The document reviewed the use of synthetic polypeptides in cosmetics, emphasizing their role in anti-aging skincare. It categorized anti-wrinkle peptides into signal peptides, neurotransmitter-affecting peptides, and carrier peptides, each with specific functions like stimulating collagen production, relaxing facial muscles, and delivering essential minerals. Notable peptides like Matrixyl® and Argireline® were discussed for their anti-aging benefits. While peptides showed promise in improving skin hydration and appearance in vitro, their in vivo efficacy remained uncertain due to absorption challenges.
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