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This study found that cationic vesicles enhanced minoxidil skin retention and in vivo hair growth efficacy compared to other formulation types due to electrostatic interactions with the skin.

This review discusses various nanocarriers for gene and genome editing therapies, highlighting that ionizable lipid nanoparticles show advanced delivery performance, while emerging polymer-based and exosome-inspired carriers are rapidly advancing for targeted applications.

In this study, researchers observed that dietary vitamin D intake and light exposure play a crucial role in vitamin D metabolism in mice, suggesting similar importance for human health in maintaining optimal vitamin D levels.

This study found that puppies fed organic selenium had better retention of selenium compared to those fed inorganic selenium, with no significant difference in coat quality or hair growth.

This study found that the ethyl acetate extract of Fagraea berteroana fruits and its fraction FEAE-F0 promoted cell proliferation and modulated gene expression in hair follicle cells, suggesting potential for hair growth stimulation.

This study concluded that two different pharmaceutical formulations of finasteride were bioequivalent in terms of rate and extent of absorption based on pharmacokinetic evaluations in a randomized crossover study with 38 volunteers.

This study analyzed the lipid composition of mouse hair, focusing on sphingolipids, and found significant differences in ceramides, glucosylceramides, and sphingomyelins between hair follicles and hair shafts.

This review discusses the therapeutic potential and challenges of using extracellular vesicles derived from mesenchymal stem cells, concluding that they may have a comparable therapeutic potential to the original cells despite current challenges in their application and production.

In this study, researchers analyzed 355 clinical trials from ClinicalTrials.gov, initiated by the end of 2025, to provide insights into the use of extracellular vesicles as circulating biomarkers or therapeutic interventions, highlighting current research priorities and future trends.

This study developed a novel LC-ESI-MS/MS method to quantify Minoxidil in pharmaceutical forms, finding it precise, accurate, and robust. It withstands excipient and degradant interference, although Minoxidil degrades under some stress conditions but remains stable thermally.

This review highlights that bacteriophage therapy shows promise for acne treatment by specifically targeting Cutibacterium acnes, but larger clinical trials and improved regulatory frameworks are needed for further development.

This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.

This review highlights that disturbances in neuroimmune communication, particularly between sympathetic nerves and macrophages, may contribute to autoimmune diseases like rheumatoid arthritis and type 1 diabetes, and suggests potential therapeutic avenues by restoring this communication in preclinical and early clinical studies.

This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.

In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.

This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.

This literature review reports that mesenchymal stem cell-derived secretome, including conditioned medium and extracellular vesicles, shows promise as an effective treatment for various diseases in animal and human in-vivo models, with ongoing clinical trials and recommendations for future research discussed.

This review highlights the potential of extracellular vesicles derived from medicinal plants as therapeutics for diseases such as cancer and inflammation, suggesting they may enhance the clinical use of herbal preparations, despite the challenges posed by extract complexity and individual variability.

In this study, isotretinoin treatment for acne vulgaris was associated with changes in plasma phosphorus, potassium, magnesium, and zinc levels, potentially affecting kidney function and contributing to side effects like fatigue and dry skin.

This study reviews the regenerative potential and clinical applications of exosomes derived from mesenchymal stem cells in conditions like COVID-19, alopecia, skin aging, and osteoarthritis, highlighting their role as a promising tool in regenerative medicine.

Innovative methods are reducing animal testing and improving biomedical research.

This review article describes the ingredients and evaluation tests for formulating a hair serum aimed at improving hair growth and preventing hair loss, highlighting the roles of Citrus sinensis, Nigella sativa, flax seed, and coconut oil in addressing hair and scalp health.

In this study, researchers analyzed a herbal shampoo containing Momordica charantia extract and Hibiscus Rosa-Sinensis, noting it could support collagen development and hair growth. The shampoo, tailored to various hair and scalp conditions, was confirmed free of certain harmful heavy metals.

This study presents a method using liquid chromatography tandem mass spectrometry to quantify biotin in plasma and serum, and explores how high biotin intake can interfere with diagnostic immunoassays that utilize biotin-streptavidin technology, potentially leading to misdiagnosis of endocrine disorders.

This review discusses the potential of exosomes and the secretome in stem cell-based regenerative therapies but reports no new experimental findings.

This study found that many effects previously thought to be caused by circadian rhythm disruption in Bmal1 knockout mice are actually due to BMAL1's properties unrelated to its clock function.

This study found that baicalin delivery through polymeric nanocapsules significantly enhanced its anticancer activity in breast cancer cell lines MCF-7 and MDA-MB-231.

This review discusses niosomes' increasing popularity in dermatology for topical drug delivery due to their ability to enhance drug penetration, provide sustained release, and carry various drugs, while reporting no new clinical findings.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.