Effects of Diet Supplementation with Sodium Selenite and Selenium-Enriched Yeast on Puppies’ Health Performance from Post-Weaning to Adulthood

This study compared the effects of two selenium sources, organic selenium from Saccharomyces cerevisiae (SeOrg) and sodium selenite (SeInorg), on the health performance of 12 Beagle puppies from 12 to 52 weeks of age. Results showed that puppies fed SeInorg had higher nutrient and energy intakes and better digestibility of crude protein and neutral detergent fiber, while SeOrg promoted higher weight gain. Plasma selenium levels were similar for both sources, but SeInorg tended to increase glutathione peroxidase activity. SeOrg showed better selenium retention, indicated by lower urinary content and fractional clearance. No significant differences were observed in coat quality and hair growth between the two selenium sources. The study suggested that organic selenium might offer better retention and less waste, warranting further research on its biological benefits.