January 2008 in “Chinese Journal of Spectroscopy Laboratory” This study utilized a fluorescence probe to evaluate cysteine formation on hair fibers, finding that optimal fluorescence emission occurred at pH 4.5.
January 2016 in “International journal of advanced research in chemical sciences” This study developed a new spectrophotometric method to accurately measure finasteride levels in pharmaceutical formulations using a reaction with NBD-CL.
This study found that culturing fibroblasts on stiffer substrates mimicking fibrotic wounds led to an aligned EDA fibronectin matrix with thinner fibers and decreased YAP activity, suggesting disrupted signaling that might be restored to promote regenerative wound repair.
142 citations
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March 2019 in “Molecules/Molecules online/Molecules annual” This review discusses the role of the endocannabinoid system in skin health and disease, highlighting its potential for future research and applications, but reports no new experimental results.
44 citations
,
April 2023 in “Frontiers in Molecular Biosciences” This narrative review outlines the diverse symptoms and possible mechanisms behind long COVID, such as immune dysregulation and viral persistence, while discussing ongoing and potential treatments, highlighting the current lack of proven effective therapies.
1 citations
,
December 2022 in “Pharmaceutics” This study found that finasteride-loaded microemulsions using poloxamer 124 significantly enhanced skin penetration of the drug compared to a standard solution, primarily through targeting hair follicles via the transfollicular pathway, with intercluster, intercellular, and transcellular pathways contributing less.
4 citations
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March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
119 citations
,
June 2005 in “Journal of Molecular and Cellular Cardiology” This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.
11 citations
,
September 2021 in “Journal of molecular endocrinology” This review discusses differences in ERβ signaling between rodents and humans and reports no new clinical results; the authors highlight the need for further research in humans before using ERβ agonists clinically.
320 citations
,
December 2018 in “Frontiers in Immunology” This review explores how preconditioning mesenchymal stromal cells can impact their secretome's therapeutic potential in regenerative medicine, emphasizing immunomodulatory and regenerative functions, but provides no new clinical results.
1 citations
,
May 2017 in “InTech eBooks” This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.
1 citations
,
March 2023 in “Phytochemistry Reviews” This review discusses the potential of CBD for treating skin disorders, the challenges of its topical administration, and current strategies to improve its application, but reports no new clinical findings.
41 citations
,
July 2018 in “Frontiers in Neurology” This study suggests that myotonic dystrophies may qualify as segmental progeroid disorders due to molecular and clinical similarities with typical progeroid syndromes.
55 citations
,
October 2020 in “Frontiers in Pharmacology” This review discusses the role of endolysosomes in SARS-CoV-2 infection and COVID-19 pathogenesis, and explores potential therapeutic strategies targeting these cellular structures, but reports no new clinical findings.
13 citations
,
November 2021 in “Frontiers in Molecular Biosciences” This review discusses the mechanisms of platinum-induced peripheral neuropathy related to reactive oxygen species and explores potential antioxidant therapies and nanotechnology approaches, but reports no new clinical results.
4 citations
,
April 2025 in “Frontiers in Immunology” This article discusses the potential of extracellular vesicles for developing precise psychiatric therapies and the need for interdisciplinary collaboration, but reports no new clinical results.
1 citations
,
August 2025 in “Frontiers in Neuroscience” This review discusses cellular senescence in relation to ALS and explores how targeting senescent cells could potentially serve as a treatment strategy, but it reports no new clinical findings and emphasizes that this link is not yet conclusively established.
October 2023 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in patient care and optimizing treatment outcomes.
January 2026 in “Health Science Reports” This study highlights a complex link between hair care and HFRBDs and suggests that personalized hair care strategies could improve condition management and be integrated into professional guidance by clinicians and hair experts.
73 citations
,
February 2023 in “Polymers” This review discusses the unique properties, design, and fabrication of peptide hydrogels for biomedical applications, focusing on advances in drug delivery, gene therapy, and regenerative medicine; it reports no new clinical results.
39 citations
,
April 2020 in “IntechOpen eBooks” The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.
1 citations
,
March 2024 in “Signal transduction and targeted therapy” In this review, researchers explored the multifaceted role of NF-κB signaling in various biological processes and diseases, including its interactions with other pathways, and discussed possible therapeutic approaches targeting this pathway for treating conditions like cancer, autoimmune disorders, and COVID-19.
48 citations
,
June 2014 in “Neurobiology of Disease” This study found that stem cells derived from spinal and bulbar muscular atrophy patients exhibited reduced androgen receptor levels and HDAC6, providing potential insights into the disease mechanism for future therapies.
26 citations
,
September 2018 in “Neurobiology of Disease” This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.
20 citations
,
April 2022 in “Frontiers in Bioengineering and Biotechnology” This review highlights the potential of regenerative medicine therapies, particularly stem cells, in treating a range of chronic diseases and injuries, while also discussing advancements and limitations in their application in Malaysia compared to other Asian countries.
9 citations
,
May 2025 in “Stem Cell Research & Therapy” This review discusses how extracellular vesicles play a dual role in age-related diseases by contributing to both disease pathogenesis and potential therapeutic strategies through the transfer of specific molecules.
5 citations
,
April 2024 in “ACS Chemical Neuroscience” This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.
September 2025 in “Frontiers in Pharmacology” This study suggests that P. orientalis leaf-derived EVs could offer anxiolytic, antidepressant, and sleep-inducing benefits by affecting neurotransmitter levels and reducing inflammation, particularly when administered intranasally.
14 citations
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November 2014 in “European journal of medicinal chemistry” This study identified 30 new compounds with significant androgen receptor binding affinity through a combination of virtual screening and in vitro testing.
February 2026 in “Journal of Dermatology and Skin Science” This review highlights that obsessive-compulsive disorder and body-focused repetitive behaviors are increasingly encountered in dermatology, often going undetected, and emphasizes the role of dermatologists in early identification and interdisciplinary treatment to address both physical and psychological aspects for improved outcomes.