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Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

Hair and nails are similar keratin structures with different shapes and growth, affected by the same diseases and environmental factors.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Mice with more Flightless I protein grew back their claws better after amputation.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

HOXC13 is essential for hair and nail development by regulating Foxn1.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.

HIV can cause hair loss and changes in nails, which may indicate disease progression.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The study found that skin conditions in COVID-19 patients can signal serious internal organ damage and may be life-threatening.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

A baby with KID syndrome died from infections and organ failure at 18 months old.

A child with ectodermal dysplasia-syndactyly syndrome has a new mutation in the NECTIN4 gene.

Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Alopecia areata is an unpredictable autoimmune hair loss condition, treated based on severity, with half of patients regrowing hair within a year without treatment.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

The study identified the top 10 most important areas for future hair loss research.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

A COVID-19 patient had unusual nail discoloration and nail separation possibly due to the virus's effects on small blood vessels.

Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.

Fish scale-based organic hair oil and shampoo may improve hair health and prevent damage.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.

Lab-grown nail cells show characteristics similar to natural nail and hair.