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Glossary Nail Psoriasis

condition where psoriasis affects fingernails and toenails, causing pitting

Nail psoriasis, also known as psoriatic nail disease, is a condition where psoriasis affects the fingernails and toenails. It can cause a variety of symptoms, including pitting (small dents) in the nails, discoloration, thickening, and separation of the nail from the nail bed (onycholysis). This condition is often associated with psoriatic arthritis and can significantly impact nail appearance and function.

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Research

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research Case of de novo nail psoriasis triggered by the second dose of Pfizer-BioNTech BNT162b2 COVID-19 messenger RNA vaccine

28 citations , September 2021 in “JAAD Case Reports”

This study reports that the Pfizer-BioNTech COVID-19 vaccine showed 52% protection against COVID-19 after the first dose and 95% after the second in phase 3 trials.

research A comparative study of Fractional co2 laser combined with topical methotrexate versus Fractional co2 laser combined with topical [Calcipotriol + Betamethasone] in the treatment of nail psoriasis

2 citations , October 2021 in “QJM”

This study found that both CO2 laser combined with topical methotrexate and calcipotriol plus betamethasone treatments improved nail psoriasis similarly, but some symptoms showed no improvement.

research 151 High effectiveness of tildrakizumab over 52 weeks in patients with or without nail psoriasis: results from the phase IV POSITIVE Austrian subset

November 2024 in “Journal of Investigative Dermatology”

Tildrakizumab significantly improved psoriasis symptoms and well-being over 52 weeks.

research From the Cochrane Library: Interventions for Nail Psoriasis

March 2025 in “Dermatology”

Systemic therapies improve nail psoriasis but have high side effects; more research is needed.

research Videodermoscopy of the hyponychium in nail bed psoriasis

76 citations , March 2008 in “Journal of the American Academy of Dermatology”

This study found that videodermoscopy can help diagnose nailbed psoriasis by revealing distinctive hyponychial capillary patterns, which correlated with disease severity and response to treatment.

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community Losing a ton consistently after 8 months dut please help me I don’t know what to do anymore, nothing works

in Chat 76 upvotes 1 year ago

A 20-year-old is experiencing hair loss despite using dutasteride and oral minoxidil. Suggestions include consulting a specialist, considering RU58841, and checking for other conditions and vitamin deficiencies.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community The final nail in the coffin. PP405 is confirmed JXL069.

440 upvotes 1 month ago

PP405 and JXL069 are confirmed to be the same molecule, leading to disappointment due to poor hair regrowth results. Users express skepticism about the credibility of Pelage and the effectiveness of JXL069.

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Clinics

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Hair Loss Treatments
Dr Michaels Psoriasis & Skin ClinicHanoi · VN

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