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GlossaryOnycholysis

nail detaches from nail bed, often due to trauma

Onycholysis is a condition where the nail separates from the nail bed, usually starting at the tip and progressing towards the cuticle. This detachment can be caused by trauma, infections, or underlying health issues such as thyroid disease or psoriasis. It often results in a white or yellowish appearance under the affected nail.

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research Acute Bullous Dermatosis and Onycholysis Due to High-Dose Methotrexate and Leucovorin Calcium

21 citations, August 1987 in “Archives of Dermatology”

High-dose methotrexate can cause severe skin and nail issues.

research Severe Onycholysis in a Card Illusionist with Alopecia Areata Universalis

10 citations, January 2013 in “International Journal of Trichology”

Systemic steroids effectively treated severe nail issues in a card illusionist with alopecia areata.

Heterogeneous Red-White Discoloration of the Nail Bed and Distal Onycholysis in a Patient with COVID-19

research Heterogeneous Red-White Discoloration of the Nail Bed and Distal Onycholysis in a Patient with COVID-19

8 citations, May 2021 in “Journal of the European Academy of Dermatology and Venereology”

A COVID-19 patient had unusual nail discoloration and nail separation possibly due to the virus's effects on small blood vessels.

research Central Trichoptilosis With Onycholysis

6 citations, October 2006 in “International Journal of Dermatology”

Hair splitting and nail detachment are linked conditions.

research A Case of Cronkhite-Canada Syndrome with Telogen Effluvium and Onycholysis

August 2025 in “The Nishinihon Journal of Dermatology”

Prednisolone treatment improved symptoms and hair regrowth in a patient with Cronkhite-Canada Syndrome.

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