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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Finasteride effectively treats male hair loss, improving growth and density.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Taking too many vitamin and mineral supplements can cause serious health problems.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.

Juniperus plants contain compounds with potential for developing various medical treatments.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Monoolein-alginate beads help heal wounds by controlling moisture and effectively delivering adenosine to the skin.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.

Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.

Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.

Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.