Exploring Reference Values for Hair Cortisol: Hair Weight Versus Hair Protein

    October 2020 in “ Therapeutic drug monitoring ”
    Florian Lemaître, Camille Tron, Thomas H. Renard, Caroline Jézéquel, Pauline Houssel‐Debry, Damien Bergeat, Cédric Pastoret, Nicolas Collet, Antoine Petitcollin, Marie‐Clémence Verdier, Édouard Bardou-Jacquet, Christophe Camus, Karim Boudjéma, Éric Bellissant, Michel Rayar
    TLDR Lower tacrolimus levels (4-7 ng/mL) after liver transplant may be safe and improve graft and kidney function.
    The study investigated whether hair protein concentration (HPC) could serve as a reference value for hair cortisol concentration (HCC) instead of the commonly used hair weight. Involving 18 hair samples, the researchers found that HCC correlated significantly with hair sample weight (r = 0.520, P = 0.027) but not with HPC (r = 0.393, P = 0.106). Additionally, hair sample weight was a better predictor of HCC than HPC. The study concluded that hair sample weight is a more suitable reference value for HCC, recommending the standard cortisol-to-weight ratio for measuring cumulative cortisol activity in scalp hair, though the cortisol-to-protein ratio could be an alternative if hair weight is unavailable.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 7 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Male pattern baldness, and mental health

      in Finasteride/Dutasteride  330 upvotes 9 months ago
      A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

      community Does Ashwagandha cause hair loss?

      in Chat  24 upvotes 1 year ago
      User asks if Ashwagandha causes hair loss while using Finasteride and Minoxidil. Replies suggest Ashwagandha may increase shedding, but raising testosterone within normal levels likely won't significantly affect hair loss.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community [SAD UPDATE] 11 Months Topical Finasteride on TrichoSol - Hair got worse - Need Opinions

      in Progress Pictures  9 upvotes 7 months ago
      A user expressed disappointment that their hair loss worsened after 11 months using topical finasteride with TrichoSol, despite no side effects and initial signs of improvement. They asked for advice and opinions on their treatment and alternatives, with suggestions including switching to oral finasteride or dutasteride, starting minoxidil, and addressing their seborrheic dermatitis with different shampoos or medical advice.

    Similar Research

    5 / 1000+ results