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Glossary Hair Cortisol Concentration

amount of cortisol embedded in hair strands over time

Hair Cortisol Concentration (HCC) refers to the amount of cortisol, a stress hormone, that is embedded in hair strands over time. Unlike blood or saliva tests that measure cortisol levels at a single point, HCC provides a long-term record of an individual's stress levels, as hair grows approximately 1 cm per month and can reflect cortisol exposure over several months. This makes it a valuable tool for both researchers and clinicians in assessing chronic stress and related health conditions.

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Research

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research Quantifying long-term stress in brown bears with the hair cortisol concentration: a biomarker that may be confounded by rapid changes in response to capture and handling

90 citations , July 2014 in “Conservation Physiology”

This study found that hair cortisol concentration in free-ranging brown bears is influenced by handling methods, body condition, and potentially both short- and long-term stressors.

research Hair cortisol concentrations in mental disorders: A systematic review

50 citations , November 2020 in “Physiology & behavior”

This review found that patients with depression generally have higher hair cortisol concentrations compared to healthy controls, while those with PTSD tend to have lower concentrations.

research Hair dyeing, hair washing and hair cortisol concentrations among women from the healthy start study

33 citations , January 2017 in “Psychoneuroendocrinology”

This study of Danish women found no evidence linking hair cortisol concentration to hair dyeing status or the frequency of hair washing.

research Hair cortisol concentration and glycated hemoglobin in African American adults

30 citations , July 2016 in “Psychoneuroendocrinology”

research Hair Cortisol Concentration in Healthy Children and Adolescents Is Related to Puberty, Age, Gender, and Body Mass Index

24 citations , January 2019 in “Hormone Research in Paediatrics”

This study found that gender, puberty, and BMI significantly affect hair cortisol concentrations in children, suggesting these factors should be considered in future research.

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Community Join

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community 25M | 10 years of gradual hair loss | Minoxidil user | Looking for input on treatment optimization before HT

4 upvotes 9 months ago

A 25-year-old male with 10 years of hair loss is using minoxidil and considering adding finasteride or dutasteride, possibly with microneedling, to improve hair regrowth before a hair transplant. Community members suggest starting a DHT blocker immediately, considering oral minoxidil, and addressing low vitamin D and HDL levels.

community Dutasteride absolutely nukes hair DHT

in Finasteride/Dutasteride 486 upvotes 1 year ago

Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.

community Testosterone and hair loss seeming irrelevance

82 upvotes 3 years ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community Taking ashwagandha with finasteride

5 upvotes 1 year ago

Ashwagandha is used to reduce stress and improve sleep, while finasteride is taken for hair loss. Users report positive effects from ashwagandha and mixed results from finasteride, with some experiencing a slight dip in libido.

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Learn

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learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

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Clinics

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Experts

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Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas