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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.

A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.

The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.

Post-finasteride syndrome's existence is uncertain; more research needed.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

FLRG and follistatin have different roles in wound healing.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.