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GlossaryMyc Family

group of genes crucial for cell growth and division

The Myc Family refers to a group of genes that play a crucial role in cell growth, division, and differentiation. These genes, including c-Myc, N-Myc, and L-Myc, are often implicated in cancer because their overexpression can lead to uncontrolled cell proliferation.

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research Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle

45 citations, April 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.

research Reversible Activation of c-Myc in Skin

467 citations, May 1999 in “Molecular Cell”

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

research Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration

21 citations, June 2016 in “PloS one”

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hr^rh-R) in the Hairless Gene (Hr)

10 citations, January 2010 in “Veterinary pathology”

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

research Melanocytes and Vitiligo and Hair Graying

1 citations, January 2014 in “Elsevier eBooks”

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

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community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 198 upvotes 2 days ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.