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GlossaryMyc Family

group of genes crucial for cell growth and division

The Myc Family refers to a group of genes that play a crucial role in cell growth, division, and differentiation. These genes, including c-Myc, N-Myc, and L-Myc, are often implicated in cancer because their overexpression can lead to uncontrolled cell proliferation.

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research Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle

45 citations , April 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.

research Reversible Activation of c-Myc in Skin

467 citations , May 1999 in “Molecular Cell”

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

research Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration

21 citations , June 2016 in “PloS one”

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

research Basal Cell Carcinomas Acquire Secondary Mutations to Overcome Dormancy and Progress from Microscopic to Macroscopic Disease

14 citations , May 2022 in “Cell Reports”

Basal cell carcinomas need extra mutations to grow from small to large tumors.

research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hr^rh-R) in the Hairless Gene (Hr)

10 citations , January 2010 in “Veterinary pathology”

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

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community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 210 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results

in Update 415 upvotes 11 months ago

ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.

community Nearly 5 months 5mg oral min, over 10 years on 1mg fin. Early-mid 30s. First photo from when I was early twenties

in Progress Pictures 1110 upvotes 10 months ago

The user experienced significant hair thickening after nearly 5 months on 5 mg oral minoxidil and over 10 years on 1 mg finasteride, with no side effects. They are considering a hair transplant for the hairline but are pleased with the current results.