Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

In this study, BALB/c mice with burn injuries treated with SES-low or SES-low combined with a gel showed better wound healing and organization compared to placebo and common treatments like silver sulfadiazine, highlighting SES-low's effectiveness in promoting favorable healing outcomes.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

This study found that low massage frequencies like 4.2 Hz enhance nanoparticle penetration into hair follicles more effectively than higher frequencies, indicating potential applications in therapeutic and cosmetic delivery.

This case report describes a 22-year-old woman with hirsutism and irregular menstrual bleeding, diagnosed with an ovarian steroid cell tumor (NOS), whose androgen levels normalized after surgery.

This study found that single-nucleus RNA sequencing identified more relevant keratinocyte clusters and specific markers than single-cell RNA sequencing, offering a new perspective on skin cell differentiation and function.

This study found that reducing BMP signaling in mouse nipple epithelia, achieved through Noggin overexpression, can convert them into hairy skin with pilosebaceous units.

This study found that in sheep, the microRNA oar-miR-377 regulates hair follicle development by targeting the SLC24A2 gene, and identified a genetic variation associated with wool quality, suggesting potential markers for breeding.

In this study, researchers investigated changes in ribosomal RNA modifications associated with stress-induced cellular senescence in human skin cells, identifying potential biomarkers and targets for interventions to mitigate skin aging.

This study found that 1064 nm QS Nd:YAG laser treatment effectively lightens hair and improves skin appearance in Indian subjects with minimal adverse effects, offering a safer alternative to chemical lightening products.

This case report describes a rare occurrence of pincer nail deformity in a patient with systemic lupus erythematosus, potentially linked to Raynaud's phenomena as a contributing factor.

This study found that human epidermal keratinocytes express a functional μ-opiate receptor at both the mRNA and protein levels, potentially playing a role in skin physiology and pathology.

This case report presents a rare instance of Winer's dilated pore in a 51-year-old female, emphasizing its pathological features and the need for accurate differential diagnosis to avoid misinterpreting it for more serious conditions.

This study identified four novel mutations in the C2orf37 gene among Woodhouse–Sakati syndrome patients, doubling known mutations, and found no significant link between isolated symptoms like deafness and dystonia and these mutations.

This study identified specific profiles and courses of adverse events associated with boron neutron capture therapy for head and neck cancer, suggesting differences based on the beam incidence site.

This case series highlighted three pediatric patients with congenital nail anomalies, revealing underlying developmental or genetic issues such as symbrachydactyly and potential Adams–Oliver syndrome, underscoring the critical role of dermatologists in early detection and diagnosis of these conditions.

This study found that surface modified nanoparticles showed increased skin permeation and improvement in allergic contact dermatitis, independent of the follicular pathway.

This study found that transgenic mice overexpressing the SSAT gene under a metallothionein promoter suffered delayed hair loss and were highly sensitive to polyamine analogues, which led to significant liver changes and mortality.

This study observed that a dual-loaded niosomal in situ gel delivered effective antimicrobial and antioxidant properties for potential ophthalmic applications, showing superior inhibition of methicillin-resistant Staphylococcus aureus adhesion.

This discussion covers various nail disorders, including tumors and non-neoplastic issues, emphasizing that not all nail abnormalities are due to fungal infections, but it reports no new clinical findings.

This study found that nanostructured lipid carriers provided better skin-targeted delivery and drug loading for lidocaine than nanoethosomes, indicating improved local anesthetic efficacy in vitro.

This study found that MSN-ceria nanomaterial accelerates cutaneous wound healing in rat models by reducing ROS levels and promoting collagen deposition, leading to improved tissue regeneration without significant scarring.

This review discusses previously reported cases of drug-associated hidradenitis suppurativa linked to various immunomodulating medications but reports no new clinical results.

This study successfully isolated inner ear-specific exosomes from perilymph samples of sensorineural hearing loss patients using a novel immunomagnetic approach, enabling groundbreaking liquid biopsy diagnostics.

This study found evidence of structurally and functionally distinct AR-SARM protein complexes, which may contribute to understanding how SARMs achieve tissue-selective effects.

This study reports a method for fabricating biofunctional polymer fibers by using DNA-programmable cell-free protein synthesis integrated through solution blow spinning, enabling in situ protein production and potential applications in respirators, sampling swabs, and other advanced materials.

Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.

This study presents a case of neuropsychiatric lupus in a 50-year-old woman, highlighting the severe impact on quality of life and the necessity for aggressive treatment to improve outcomes.