A Comprehensive Investigation Into the Molecular Mechanism Responsible for Selective Androgen Receptor Modulator Tissue-Selectivity

January 2008 in “ OhioLink ETD Center (Ohio Library and Information Network) ”

Natalie Goldberger

selective androgen receptor modulators SARMs androgen receptor AR nuclear receptor corepressor NCoR dihydrotestosterone DHT cytoplasmic-nuclear transport nuclear foci formation corepressor

Studysummary This study found evidence of structurally and functionally distinct AR-SARM protein complexes, which may contribute to understanding how SARMs achieve tissue-selective effects.

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