Identification and Expression of the Target Gene SLC24A2 of Oar-miR-377 and Its Novel SNPs Effects on Wool Traits in Sheep

    March 2024 in “ Research Square (Research Square) ”
    Huaqian Zhou, Wenhua Fan, Lixia Qiu … Wenzhe Zhang

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that in sheep, the microRNA oar-miR-377 regulates hair follicle development by targeting the SLC24A2 gene, and identified a genetic variation associated with wool quality, suggesting potential markers for breeding.
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    Research cited in this study 7

    1. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    2. Immune Privilege Collapse And Alopecia Development: Is Stress A Factor Skin Appendage Disorders · 2017
    3. Epithelial Skin Biology: Stem Cells and Epidermal Homeostasis Current Topics in Developmental Biology · 2016
    4. Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument Developmental Dynamics · 2015
    5. Leptin Controls Hair Follicle Cycling Experimental Dermatology · 2014
    6. Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation Development · 2012
    7. Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010