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120-150 / 1000+ results![Chapter 14 Principles of drug metabolism](/images/research/c12dc5d4-d3c9-408b-be08-a1f6f0cb6b51/small/23288.jpg)
research Chapter 14 Principles of drug metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
![Plain Language Summaries](/images/research/fca6c77a-15c4-4fdb-a48b-8e34cc68ece1/small/16142.jpg)
research Plain Language Summaries
Most clinicians follow discharge guidelines, many lupus patients don't use sunscreen regularly, dithranol is effective for psoriasis, biopsy methods should be based on lesion type, voriconazole may raise skin cancer risk, a new scale can help diagnose female hair loss early, and most melanomas may develop from existing moles.
![Prooxidant and antioxidant action of 4-(4-phenoxybenzoyl)benzoic acid derivatives](/images/research/b1da919c-1b20-4df5-917f-fee3bdaa24e0/small/15315.jpg)
research Prooxidant and antioxidant action of 4-(4-phenoxybenzoyl)benzoic acid derivatives
4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.
![The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review](/images/research/8e4af310-cc49-4a7b-8fa1-bf863a3619d5/small/12918.jpg)
research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review
Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
![Sulfation of minoxidil by human liver phenol sulfotransferase](/images/research/5e562f60-0bd9-4a89-9aba-d853b402f93b/small/1943.jpg)
research Sulfation of minoxidil by human liver phenol sulfotransferase
Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
![Electrochemical studies on minoxidil and its determination in tablets by differential-pulse polarography](/images/research/9499e9a7-40b0-4f0c-a1fd-70007f6016b8/small/1814.jpg)
research Electrochemical studies on minoxidil and its determination in tablets by differential-pulse polarography
Method measures minoxidil in tablets accurately and easily.
![Potential Use of Spin Traps to Control ROS in Antipollution Cosmetics—A Review](/images/research/91835be0-0be7-4f34-b1ff-5600344c255a/small/18008.jpg)
research Potential Use of Spin Traps to Control ROS in Antipollution Cosmetics—A Review
Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
![Minimum Structural Requirements for Minoxidil Inhibition of Lysyl Hydroxylase in Cultured Fibroblasts](/images/research/032c8077-6140-47e6-bb0e-5ee6243d4cbb/small/2018.jpg)
research Minimum Structural Requirements for Minoxidil Inhibition of Lysyl Hydroxylase in Cultured Fibroblasts
Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.
![Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen](/images/research/4bf69b4d-2b2e-400c-87f0-4798d75362c9/small/12602.jpg)
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
![Examining the Effect of Notocactus ottonis Cold Vacuum Isolated Plant Cell Extract on Hair Growth in C57BL/6 Mice Using a Combination of Physiological and OMICS Analyses](/images/research/f2df75d7-7412-4ea0-ba8b-7da99b422e4e/small/22781.jpg)
research Examining the Effect of Notocactus ottonis Cold Vacuum Isolated Plant Cell Extract on Hair Growth in C57BL/6 Mice Using a Combination of Physiological and OMICS Analyses
Cactus extract from Notocactus ottonis may help promote hair growth.
![Development and Validation of RP-HPLC Method for Simultaneous Estimation of Minoxidil and Aminexil in Topical Formulation](/images/research/8089e62d-6afa-4622-85f9-e923334d9ec4/small/14023.jpg)
research Development and Validation of RP-HPLC Method for Simultaneous Estimation of Minoxidil and Aminexil in Topical Formulation
A new method was created to accurately measure minoxidil and aminexil in hair loss treatments.
![Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles](/images/research/edfb7499-22c8-46c4-891f-87ecc8b32ff0/small/1954.jpg)
research Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles
Minoxidil works in liver and outer hair root sheath for hair growth.
![FORMULATION AND EVALUATION OF MINOXIDIL GEL IN COMBINATION WITH ALOE VERA FOR TOPICAL APPLICATION FOR THE TREATMENT OF ALOPECIA](/images/research/638bae1a-3566-418d-a099-31d00c9dfedf/small/20602.jpg)
research FORMULATION AND EVALUATION OF MINOXIDIL GEL IN COMBINATION WITH ALOE VERA FOR TOPICAL APPLICATION FOR THE TREATMENT OF ALOPECIA
The gel combining minoxidil and Aloe vera could be an effective, non-irritating treatment for hair loss.
![Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil:<i>in vitro</i>evaluation of drug permeation by infrared spectroscopy](/images/research/7ece98c0-d3b0-44d0-86c4-96453e0f94cc/small/3347.jpg)
research Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil:in vitroevaluation of drug permeation by infrared spectroscopy
PEVs effectively deliver minoxidil through skin.
research A Stability Indicating UPLC Method for Finasteride and Its Related Impurities
![Minoxidil (Mx) as a prophylaxis of doxorubicin – induced alopecia](/images/research/a4978719-cc91-45f9-90de-b5a161fc7196/small/2046.jpg)
research Minoxidil (Mx) as a prophylaxis of doxorubicin – induced alopecia
Minoxidil not effective in preventing chemotherapy-induced hair loss.
![Metabolism of Minoxidil, a New Hypotensive Agent 11: Biotransformation following Oral Administration to Rats, Dogs, and Monkeys](/images/research/ea63462d-4b30-45f5-bb75-43dc3bd37636/small/1761.jpg)
research Metabolism of Minoxidil, a New Hypotensive Agent 11: Biotransformation following Oral Administration to Rats, Dogs, and Monkeys
Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
![Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution](/images/research/83337258-579e-4d4a-b473-6bac2ed8b60b/small/1937.jpg)
research Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution
Longer contact time increases minoxidil absorption, but doesn't affect metabolism.
![Solubility of Minoxidil in Methanol, Ethanol, 1-Propanol, 2-Propanol, 1-Butanol, and Water from (278.15 to 333.15) K](/images/research/61c92f83-8f5b-4e33-8e02-b63ab891e534/small/3046.jpg)
research Solubility of Minoxidil in Methanol, Ethanol, 1-Propanol, 2-Propanol, 1-Butanol, and Water from (278.15 to 333.15) K
Minoxidil dissolves best in methanol and least in water.
![Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 α increase in epidermal in vitro model](/images/research/76240276-2fa0-459c-a0c8-8d0b43e026ac/small/29084.jpg)
research Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 α increase in epidermal in vitro model
Permanent hair dye mixtures can irritate and damage the skin.
![Chromatographic Methods for the Determination of Aminexil, Pyridoxine, and Niacinamide in a Novel Cosmetic Hair Preparation](/images/research/e546af8a-82b1-4876-bd37-62ae0ce167b6/small/26668.jpg)
research Chromatographic Methods for the Determination of Aminexil, Pyridoxine, and Niacinamide in a Novel Cosmetic Hair Preparation
Two new methods accurately measure Aminexil, Pyridoxine, and Niacinamide in hair products.
![The Development of a Manipulative Spectrophotometric Technique for the Determination of Aminexil in a New Hair Tonic Preparation](/images/research/d9a0f2a2-ba22-4bc7-ad7f-1a26d5177ee4/small/26839.jpg)
research The Development of a Manipulative Spectrophotometric Technique for the Determination of Aminexil in a New Hair Tonic Preparation
Researchers developed a simple, low-cost method to accurately measure Aminexil in hair tonic.
![Minoxidil: a review of its pharmacological properties and therapeutic use.](/images/research/240d148d-9c8d-43f8-ae94-e7f73fe07cba/small/1808.jpg)
research Minoxidil: a review of its pharmacological properties and therapeutic use.
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
![The history of the development of minoxidil](/images/research/be333221-b048-4186-9caa-d9873deaf721/small/1894.jpg)
research The history of the development of minoxidil
Minoxidil was first made for high blood pressure, but it was later found to help hair growth.
![Adsorptive cathodic stripping determination of minoxidil in pharmaceutical, cream and shampoo products](/images/research/0c25a8cc-367e-48dc-bfe2-c8ec7caec5a2/small/28440.jpg)
research Adsorptive cathodic stripping determination of minoxidil in pharmaceutical, cream and shampoo products
Researchers developed a sensitive method to measure minoxidil in various products with high accuracy.
![Scaled Quantum Chemical Studies of the Molecular Structure and Vibrational Spectra of Minoxidil](/images/research/3bf8798c-17c6-4034-8663-a714e8da4835/small/18798.jpg)
research Scaled Quantum Chemical Studies of the Molecular Structure and Vibrational Spectra of Minoxidil
The analysis shows where minoxidil's atoms are likely to react and describes its electronic transitions and behavior with temperature changes.
![Monocyclic Aromatic Compounds](/images/research/440aa389-c6b1-4abc-a558-ed14d52b371d/small/20412.jpg)
research Monocyclic Aromatic Compounds
Monocyclic aromatic compounds are important for developing various drugs and treatments.
![Hormone Blocking Anticancer Drugs](/images/research/95418b44-ada7-42b3-bfc5-595ec78685b7/small/20267.jpg)
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
![Cosmeceuticals](/images/research/6e479173-cca4-47b6-b104-1b8f794b58b4/small/15333.jpg)
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.