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Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Some synthesized peptides improved cell growth better than thymosin β4, VEGF, and minoxidil.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.

PAD is common but often missed, needing lifestyle changes and medication for better outcomes.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Large-scale fibronectin nanofibers help heal wounds and repair tissue in a skin model of a mouse.

New therapies are being developed that target integrin pathways to treat various diseases.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.

Women may need different blood pressure guidelines than men for heart disease prevention.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.

Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Metabolic syndrome is more common in people with early-onset androgenic alopecia.

Genetics and nutritional deficiencies are key factors in premature graying of hair.