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Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

The textbook "Dermatology" is highly recommended for its comprehensive content, user-friendly design, and extensive visual aids.

Mutations in hKAP1 genes may cause hereditary hair disorders.

A boy with monilethrix has brittle hair that breaks easily due to a genetic condition, which might improve by puberty.

Monilethrix has no effective treatment, but avoiding hair trauma helps manage it.

HOXC13 is essential for hair and nail development by regulating Foxn1.

Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Researchers made a mouse model with curly hair and hair loss by editing a gene.

FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Keratin mutations cause skin diseases and could lead to new treatments.

Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.

The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.

A baby girl has a hair disorder called monilethrix, causing fragile hair that may improve over time.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.