February 2024 in “PubMed” This study reported that minoxidil lotions produced using a propylene glycol-free base, Aloplus Total, demonstrated high minoxidil solubility and maintained chemical and physical stability for over 180 days, suggesting suitability for enhanced topical treatments of androgenetic alopecia.
3 citations
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March 2005 in “Iranian Journal of Pharmaceutical Sciences” This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.
January 2020 in “한국미용학회지” This study found that incorporating Musa extracts in pretreatment products effectively mitigated hair damage during permanent wave application, closely maintaining hair thickness and tensile strength compared to untreated hair.
7 citations
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February 2010 in “British Journal of Dermatology” A woman with a rare autoimmune disorder had a blister on her eye and unique immune reaction, which was effectively treated with medication.
1 citations
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January 2025 in “Regenerative Biomaterials” In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.
October 2025 in “Carbohydrate Polymer Technologies and Applications” This study investigated improving Finasteride's water solubility using trimethyl-β-cyclodextrin (TM-β-CD) and β-cyclodextrin (β-CD) as carriers, finding that β-CD improved Fin's cumulative release, while TM-β-CD enhanced its solubility, with computational data supporting these outcomes.
22 citations
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March 2007 in “European journal of pediatrics” This study found that scanning electron microscopy revealed considerable abnormalities in hair morphology in MPS I, II, IIIA, and IIIB patients, potentially related to heparan sulfate accumulation.
April 2025 in “Journal of Advances in Medical and Pharmaceutical Sciences” This review highlights the potential of spanlastics, a new type of drug delivery system, to enhance drug administration by offering better deformability and stability compared to other nanocarriers, potentially improving targeted drug delivery across various applications.
November 2025 in “Drug Delivery and Translational Research” 5 citations
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April 2014 in “Journal of Lipid Research” This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.
December 2015 in “Focus on catalysts” This study found that Pomiferin demonstrated potent stimulation of extracellular matrix proteins in human dermal fibroblasts and hair follicles, suggesting its potential as an ingredient in skin and scalp treatments.
48 citations
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June 1988 in “PubMed” In this study, minoxidil sulfate was found to relax norepinephrine-induced contractions in rabbit mesenteric arteries, possibly by acting as a K+ channel agonist, but it did not relax K+-induced contractions.
2 citations
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May 2025 in “Skin Appendage Disorders” This review highlights the benefits and controversies of silicones in hair care, emphasizing their ability to improve hair texture and moisture retention while addressing environmental concerns and product buildup.
April 2025 in “Jurnal Sains dan Teknologi Farmasi Indonesia” This study found that a nanostructured lipid carrier gel containing Minoxidil and Finasteride met desired criteria for stability and performance, suggesting it may be an effective topical treatment for hair loss, especially in extreme conditions.
5 citations
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February 2010 in “Drug development and industrial pharmacy” This study found that vesicles formed with behenyltrimethylammonium chloride, stearic acid, and hinokitiol significantly improved skin permeation of hinokitiol in vitro, which may aid in hair growth promotion.
6 citations
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December 2015 in “International journal of nanomedicine” This study found that low-frequency sonophoresis significantly decreased the skin penetration of sodium fluorescein-loaded PEGylated liposomes with D-limonene and affected percutaneous absorption by partially plugging hair follicle orifices.
40 citations
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March 2022 in “Small” In an animal model, this study found that PEG hydrogels delivering M2 macrophage-derived exosomes effectively promoted M1 to M2 macrophage transition and enhanced wound healing.
April 2023 in “International Journal of Pharmaceutics” In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.
May 2026 in “Journal of Cosmetic Dermatology” This narrative review found that skin boosters, including hyaluronic acid and other agents, improve skin hydration, elasticity, and texture with favorable safety, though evidence is limited by study heterogeneity and lacks standardized protocols, suggesting a need for further clinical research.
June 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study suggests that MUC1 expression is significantly higher in follicular mucinoses compared to other dermal mucinoses, particularly in lymphoma-associated forms, indicating its potential as a target for immunotherapy.
54 citations
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January 1984 in “Molecular and Cellular Biochemistry” 59 citations
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September 2021 in “Cosmetics” This review discusses lipid nanoparticle-based cosmetics, emphasizing their potential in protecting skin from radiation and treating conditions like atopic dermatitis and psoriasis with synthetic and natural antioxidants. It highlights recent research on these formulations' effectiveness in alleviating skin disorders and enhancing skin health.
April 2015 in “한국고분자학회 학술대회 연구논문 초록집”
1 citations
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June 2019 in “International Journal of Applied Pharmaceutics” In this study, nanostructured lipid carriers for hair split-end repair showed similar efficacy regardless of charge, with negatively charged carriers exhibiting better stability over six months compared to positively charged ones.
1 citations
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May 2022 in “International Journal of Health Sciences (IJHS) (En línea)” This research reports the presence of various physicochemical constituents and nutrients in glycine max (soybean) milk and okara, highlighting its potential medicinal and nutritional benefits.
23 citations
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June 2017 in “Drug Design Development and Therapy” This study found that the dimethyl-β-cyclodextrin inclusion system significantly improved the solubility and bioavailability of finasteride compared to the drug alone, enhancing its absorption rate.
November 2004 in “Qucosa (Saxon State and University Library Dresden)” This study developed analytical methods to better understand hair treatment with cosmetic formulations, revealing that active agents primarily adsorb on the hair surface during short washes.
2 citations
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December 1994 in “International Journal of Cosmetic Science” In this study, the combination of biologically engineered hyaluronic acid and polyquaternium-10 improved hyaluronic acid's retention and moisturizing effects on hair by forming a stable complex that increased binding affinity to keratin.
March 2024 in “International journal of molecular sciences” This study found that human meibomian glands differ significantly from free and hair-associated sebaceous glands in morphology and lipid composition, making them highly specialized holocrine glands.
1 citations
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January 2008 in “Massey Research Online (Massey University)” This study found that enzyme depilation of lambskins can cause damage due to the removal of collagen VI, suggesting the need for a protease that avoids this interaction for successful application.