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This study found that the p.E402K mutation in the KRT86 gene is a hotspot in Chinese patients with monilethrix, and treatment with 5% topical minoxidil significantly improved hair density and quality.

In this case report, a 62-year-old postmenopausal woman with hyperandrogenism exhibited male-pattern alopecia and hirsutism, which improved after bilateral adrenal adenomas were removed, underscoring the need for investigation of androgen-producing tumors in similar cases.

This study suggests that in an ex vivo rat glaucoma model, TSPO activation is involved in Allopregnanolone synthesis and may help prevent retinal damage, with TSPO agonists as potential therapeutic agents.

This study describes the first case of female pseudohermaphroditism due to a novel homozygous glucocorticoid receptor gene mutation, indicating possible pre- and postnatal virilization in affected females.

This article discusses the complexities of diagnosing hyperandrogenism in women and reviews potential treatments, such as antiandrogens and finasteride, but reports no new clinical findings.

This study found that multiple ion channel modulators, used here at clinical concentrations, increased intracellular calcium release in prostate and breast cancer cell lines.

This review discusses the role of transient receptor potential channels in pathological scarification and suggests these channels as potential targets for its prevention and treatment, although it reports no new clinical findings.

New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.

This case report describes a patient with an ovarian steroid cell tumor that initially presented as non-classical adrenal hyperplasia, emphasizing the difficulty in differential diagnosis with hyperandrogenism and the importance of close clinical monitoring.

In this study, the researchers used a human hair follicle model to demonstrate that T cell stimulation can induce an alopecia areata–like phenotype, with cell proliferation and immune privilege collapse; however, the DHODH inhibitor farudodstat partially mitigated these effects by reducing T cell proliferation.

In this case report, tamoxifen-induced hirsutism was observed in a young girl with McCune-Albright syndrome shortly after starting treatment.

In this case report, a young man with primary hypothyroidism caused by autoimmune atrophic thyroiditis showed full recovery and normalization of metabolism after levothyroxine treatment.

Senescent melanocytes in nevus skin boost hair growth.

In this study, YK11 was found to promote osteoblast cell proliferation and differentiation through activation of non-genomic signaling pathways in mouse osteoblast cells.

This case series found that low-frequency repetitive transcranial magnetic stimulation may benefit some patients with trichotillomania, although one of five patients experienced worsening symptoms after treatment.

This review discusses the roles of key epithelial-mesenchymal transition factors and potential therapeutic opportunities involving cancer metabolic pathways, reporting no new clinical results.

This study reported that patients with PCOS and thyroid hormone disturbances had specific TPO gene mutations and differing thyroid hormone levels compared to those without disturbances or healthy controls.

This report describes a case where a 44-year-old male treated with vorasidenib for diffuse low-grade gliomas developed unexpected hair growth, including in areas of severe hair loss, after one month, highlighting a previously undocumented side effect.

This study found that activating hair follicle resident T cells in a human organ culture can induce an alopecia areata-like immune response, and that the drug farudodstat partially reduced this effect.

This study found that activating autophagy with specific small molecules and drugs can stimulate hair growth by initiating the anagen phase in dormant hair follicles, suggesting a potential treatment for hair loss.

This study found that girls with prepubertal simple hypertrichosis had significantly higher plasma levels of dihydrotestosterone compared to controls, which does not align with other androgen markers and warrants further investigation.

A woman's hyperandrogenism was caused by a genetic mutation leading to non-classic adrenogenital syndrome.

This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.

In this study, crossing mice overexpressing antizyme with MEK mutants significantly delayed tumor development and reduced tumor frequency, likely by slowing cell growth in skin tumors.

This case report describes the first known instance of a testosterone-secreting steroid cell ovarian tumor causing pulmonary embolism and erythrocytosis in a postmenopausal woman, highlighting its potential role as a rare cause of hypercoagulable state.

Stopping methotrexate might reverse lymphoma-like conditions in some patients.

This case study suggests that genetic susceptibility to PCOS and rare syndromes, such as Trichorhinophalangeal syndrome Type 1, should be considered in young men with unexplained hyperandrogenism.

This article discusses clinical features and treatment options for hyperandrogenism in women and does not report new findings, highlighting current practices in diagnosis and management.

This study observed that Greek Caucasian women with PCOS had distinct serum hormone levels and a specific AKT2 gene SNP, which may play a role in the condition's characteristics.

Oxidative stress and mitophagy play key roles in hair loss, suggesting potential treatment targets.