Tamoxifen-Associated Hirsutism: An Unusual Side Effect in a 5-Year-Old Girl with McCune-Albright Syndrome

January 2015 in “ Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism ”

Heves Kırmızıbekmez, Gül Yeşiltepe Mutlu, Fatma Dursun, Şükriye Pınar İşgüven

tamoxifen hirsutism McCune-Albright syndrome peripheral precocious puberty selective estrogen receptor modulator Nolvadex

TLDR A 5-year-old girl with McCune-Albright syndrome grew abnormal hair due to the drug tamoxifen.

A 5-year-old girl with McCune-Albright syndrome experienced unusual hair growth (hirsutism) approximately 2 months after starting tamoxifen treatment for peripheral precocious puberty. The pattern of terminal hair growth and the exclusion of other potential causes indicated that the hirsutism was induced by tamoxifen, a selective estrogen receptor modulator. This case highlighted an uncommon side effect of tamoxifen in pediatric patients.

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community My Experience With Finasteride

in Research/Science 21 upvotes 1 year ago

A user shared their experience with Finasteride for hair loss, noting a significant reduction in DHT levels and a complete loss of libido without other side effects. Another user agreed, discussing the negative impact on sexual drive and criticizing the community's attitude towards discussing side effects.

community Gyno & testoterone level

in Finasteride 282 upvotes 6 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

community Treatment of Finasteride Induced Gynecomastia (Male breast tissue growth)

in Finasteride/Dutasteride 15 upvotes 4 years ago

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community How long would dermarolling and minoxidil work for if you can’t use finasteride? 24m mild diffuse thinning up to crown

in Treatment 8 upvotes 3 years ago

Long-term efficacy of dermarolling with minoxidil is discussed for hair loss treatment. User can't use RU, Fin, or topical Fin due to side effects and considers using finasteride with an aromatase inhibitor as a last resort.

community What happens to the excess testosterone after using dut?

in Finasteride/Dutasteride 23 upvotes 3 weeks ago

Using dutasteride or finasteride can increase free testosterone, which may convert to estradiol, potentially causing side effects like increased estrogen levels. Individual responses vary, and some users report changes in cholesterol, hair texture, and side effects like gyno or increased sex drive.

community 3 month into 2.5mg dutasteride - no hairs fall out of my head anymore

in Technology 37 upvotes 2 months ago

OP reports that after 3 months on 2.5mg dutasteride, their hair has stopped falling out and is thick again, but they are considering stopping due to potential mood and energy side effects. Other users discuss experiences with finasteride, dutasteride, and side effects, with some suggesting lower doses or alternative treatments like topical applications.

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