Severe Hirsutism in Non-Classic Congenital Adrenal Hyperplasia: A Case Report and Literature Review

The document reported a case of a 27-year-old girl who had been experiencing severe hirsutism, hair loss on the front of the scalp, breast volume reduction, weight loss of 15 kg, and depression for 2 years. Despite using oral contraceptives for over a year, her condition did not improve. Blood tests revealed high levels of 17 (OH) progesterone and all other androgen hormones, leading to a diagnosis of non-classic congenital adrenal hyperplasia (NCAH). After starting treatment with corticosteroids and other necessary treatments, the patient's clinical and hormonal features improved. This case highlighted the importance of considering NCAH in the differential diagnosis of patients presenting with symptoms of excessive androgen secretion.