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Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Melatonin protects skin against UV damage by regulating various cellular processes.

Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

Sp6 promotes tooth development by reducing follistatin levels.

Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

MED1 affects skin wound healing differently in young and old mice.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.