12 citations
,
February 2023 in “Stem Cell Research & Therapy” This study found that injecting hepatocyte growth factor-enhanced hair follicle stem cells into a rat model of ischemic stroke improved recovery by reducing inflammation, protecting the blood-brain barrier, and promoting angiogenesis.
12 citations
,
September 2022 in “Frontiers in Immunology” This study found that soluble CD83 (sCD83) accelerated chronic and hard-to-heal wound healing and improved inflammatory and pro-resolving cytokine profiles, suggesting potential for therapeutic use.
12 citations
,
November 2012 in “BioMolecular Concepts” This review discusses the diverse roles of PPARβ/δ in skin health and disease, including its involvement in skin wound healing and inflammatory skin conditions, without presenting new experimental results.
11 citations
,
December 2024 in “Stem Cell Research & Therapy” In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.
11 citations
,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study found that young host mice rejuvenated aged hair follicles after transplantation, while aged host mice did not support hair growth from transplanted follicles.
11 citations
,
June 2010 in “Medical Molecular Morphology” 10 citations
,
December 2023 in “International Journal of Nanomedicine” This study reviewed the challenges of delivering nucleic acids for gene therapy, highlighting the limitations of non-viral vehicles and exploring bioinspired strategies using cell membrane camouflage for improved delivery efficacy.
9 citations
,
November 2024 in “Biotechnology for Sustainable Materials” This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.
9 citations
,
September 2019 in “PLoS ONE” This study demonstrated that keratin K124 is specific to equine hoof lamellar tissue and established monoclonal antibodies that can specifically recognize K124 without cross-reacting with other tissues.
8 citations
,
January 2024 in “Regenerative Biomaterials” This study found that a novel bioceramic/alginate hydrogel with photothermal properties and multiple ion release effectively reduces infection and inflammation, and enhances osseointegration in early-stage peri-implant lesions, potentially improving dental implant survival rates.
8 citations
,
October 2021 in “Stem Cell Research & Therapy” This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.
7 citations
,
February 2023 in “Inflammation and Regeneration” This study found that IL-1α promotes hair follicle regeneration and stem cell activation in an age-dependent manner by modulating inflammatory cells and oxidative stress in mice.
7 citations
,
March 2022 in “Frontiers in Genetics” This study identified genetic loci and pathways associated with long hair growth in the Tianzhu white yak, providing new insights into the genetic mechanisms of this trait.
7 citations
,
December 2019 in “Pharmaceutics” This study found that co-administration of ketoconazole significantly altered the pharmacokinetics of dutasteride in rats, suggesting an interaction potential between dutasteride and azole antifungal drugs.
6 citations
,
November 2024 in “Frontiers in Sustainable Food Systems” This study found that ultrasonication pre-treatment at various power levels improved the color, protein solubility, and degree of hydrolysis of fish protein hydrolysates from mackerel side streams, and potentially reduced bitterness by decreasing hydrophobic free amino acids.
6 citations
,
June 2012 in “PloS one” This study identified a novel SCF mRNA splice variant in white merino sheep skin, which may play a role in hair follicle melanogenesis.
5 citations
,
July 2024 in “Frontiers in Microbiology” In this study, researchers using Mendelian randomization found a potential causal relationship between the gut microbiome and alopecia areata, with 16 gut microbial taxa showing links to the condition, though reverse causation results were not statistically significant.
5 citations
,
April 2024 in “ACS Chemical Neuroscience” This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.
5 citations
,
April 2022 in “Frontiers in Medicine” This study summarizes the signaling molecules and extracellular components involved in epithelial–mesenchymal interactions, enhancing our understanding of hair follicle regeneration and skin wound healing, but reports no new experimental results.
4 citations
,
May 2023 in “Cells” In this study, baricitinib treatment improved the differentiation of skin-derived precursors into adipocytes for diseases like Hutchinson-Gilford progeria syndrome, suggesting potential benefits when combined with lonafarnib.
4 citations
,
June 2025 in “JMIR Formative Research” In this study, researchers reported no statistically significant association between hair cortisol levels and either perceived stress or objective neuroendocrine stress measures in a predominantly male participant group.
4 citations
,
February 2023 in “iScience” This study found that unique genomic regions in Korean long-tailed chickens may contribute to their long tail feathers, offering potential for genetic advancements in ornamental chicken breeding.
4 citations
,
January 2023 in “Frontiers in Immunology” In this Mendelian randomization study, shortened leukocyte telomere length was associated with an increased risk of androgenetic alopecia, but no causal relationship was found with alopecia areata.
3 citations
,
June 2023 in “Molecules/Molecules online/Molecules annual” The researchers reviewed cepharanthine, a long-used bisbenzylisoquinoline alkaloid, for its antiviral properties, including significant inhibition of SARS-CoV-2. They discussed cepharanthine's other pharmacological actions, highlighted plasma membrane fluidity as a key antiviral mechanism, and examined its safety, bioavailability, and potential for new clinical applications.
3 citations
,
August 2022 in “Biochemical Genetics” 3 citations
,
January 2022 in “Burns & Trauma” This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.
3 citations
,
January 2021 in “Journal of Research in Medical Sciences” This review examines the interplay between metabolic syndrome and dermatologic conditions and reports no clinical results, emphasizing the need for awareness of their interconnected impacts when managing inflammatory skin diseases.
3 citations
,
October 2012 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, pemetrexed combined with cisplatin for advanced NSCLC treatment had similar efficacy to gemcitabine but resulted in significantly fewer adverse reactions.
3 citations
,
July 2025 in “Pharmaceutics” In this study, Levant Storax Cream demonstrated the highest wound healing rates in rats compared to a commercial wound care cream, a complex cream, and placebo.
3 citations
,
January 2025 in “Journal of Natural Products” In this study, researchers isolated new compounds from the plant *Calanthe cardioglossa* and found that five of these compounds, particularly calancardin B, significantly reduced TNF-α levels in immune cells relevant to multiple sclerosis, suggesting potential for immunomodulatory effects.