The Causal Relationship Between Gut Microbiota and Alopecia Areata: A Mendelian Randomization Analysis

    July 2024 in “ Frontiers in Microbiology ”
    Dezhao Bi, Jin Tong Tey, Dan Yao … Shun Guo
    Studysummary In this study, researchers using Mendelian randomization found a potential causal relationship between the gut microbiome and alopecia areata, with 16 gut microbial taxa showing links to the condition, though reverse causation results were not statistically significant.
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    Research cited in this study 8

    1. Exploring the Role of Gut Microbiota in Patients with Alopecia Areata International Journal of Molecular Sciences · 2024
    2. Exploring the Link Between Gut Microbiota and Alopecia Areata: A Two-Sample Mendelian Randomization Analysis International Journal of Dermatology · 2024
    3. The Burden of Alopecia Areata: A Scoping Review Focusing on Quality of Life, Mental Health, and Work Productivity Journal of the European Academy of Dermatology and Venereology · 2023
    4. How Our Microbiome Influences the Pathogenesis of Alopecia Areata Genes · 2022
    5. Lifestyle Factors Involved in the Pathogenesis of Alopecia Areata International journal of molecular sciences · 2022
    6. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    7. Alopecia Areata: Current Situation and Perspectives Archivos Argentinos De Pediatria · 2017
    8. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010

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    1. Serum Zinc Concentration in Patients With Alopecia Areata Acta dermato-venereologica (Print) · 2023