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Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

Hair growth and development are controlled by specific signaling pathways.

Wounded skin cells can revert to stem cells and help heal.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Laser treatment helped regrow hair in mice by activating a key growth pathway.

Hair treatments cause significant structural changes, especially with excessive heat, regardless of ethnicity.

Keratin hydrogel from human hair is a promising biocompatible material for soft tissue fillers.

We need better ways to test and understand SARMs to make safer and more effective treatments.

The exact causes of baldness are not fully understood, limiting treatment options.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Different types of atopic dermatitis were linked to specific genetic and immune changes, suggesting that severe cases might need stronger immune-targeting treatments.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Skin aging reflects overall body aging and can indicate internal health conditions.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Exosomes show promise for treating skin diseases and improving skin regeneration.

George Ernest Rogers was a notable scientist who made important discoveries about hair and wool proteins.

Personalized treatment based on detailed tumor analysis successfully managed and reduced the patient's aggressive hair follicle cancer.

Controlling Tslp can improve health in AEC syndrome patients.

Genetic manipulations that extend lifespan in mice may not work as effectively in humans.

Auxin and ethylene hormones both work together and against each other to control plant growth.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Two sisters with rickets and hair loss had a genetic issue with vitamin D processing, and only improved when given phosphorus supplements.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.