253 citations
,
April 2009 in “Journal of Biological Chemistry” This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.
68 citations
,
July 2011 in “Journal of Biochemistry/The journal of biochemistry” This review discusses newly identified non-Edg family lysophosphatidic acid receptors, detailing their roles in vascular development, platelet activation, and hair growth, and reports no clinical results.
151 citations
,
August 2011 in “The EMBO Journal” The enzyme PA-PLA1α is important for proper hair follicle development.
4 citations
,
September 2021 in “Medical Lasers” This review reports that low-level laser therapy may effectively prevent and alleviate oral mucositis from chemotherapy, supporting its use as a viable treatment option.
24 citations
,
July 2015 in “Molecular Medicine Reports” This study found that lysophosphatidic acid increases mesenchymal stem cell proliferation and migration through signaling pathways and reactive oxygen species, implicating potential applications in stem cell expansion.
December 2024 in “Biochemical and Biophysical Research Communications” LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study demonstrates that machine learning-assisted fabrication of PRP-incorporated microneedles effectively promotes hair regrowth in AGA mice, outperforming minoxidil and mitigating biosafety risks associated with synthetic materials.
6 citations
,
December 2021 in “Journal of Clinical Medicine” This study introduced the Lichen Planus Activity and Damage Index (LiPADI), which effectively assesses the severity and progression of lichen planus, aligning well with other clinical indicators.
March 2026 in “ArXiv.org” This review presents a comprehensive evaluation of medical reasoning using large language models, highlighting a significant gap between exam-level performance and true clinical decision-making accuracy.
4 citations
,
January 2014 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” This article details various skin and oral lesions through illustrative figures but does not present new research results.
2 citations
,
January 2024 in “Revista Paulista de Pediatria” In this case report, researchers described a 6-year-old girl with severe mandibuloacral dysplasia type A, noting unique physical deformities and a rare homozygous LMNA gene mutation not commonly associated with the condition.
9 citations
,
July 2010 in “British Journal of Dermatology” This article reports on lentiginosis observed within plaques of linear atrophoderma of Moulin and discusses its potential classification as a twin-spotting phenomenon but provides no new clinical research results.
66 citations
,
January 2010 in “Journal of The American Academy of Dermatology” This study reported that mycophenolate mofetil was effective in reducing signs and symptoms of active lichen planopilaris in 83% of patients who had failed multiple prior treatments.
50 citations
,
December 2010 in “Dermatologic Surgery” This study suggests that a 1,550-nm fractional erbium-glass laser may stimulate hair growth in both an alopecia mouse model and human subjects with male pattern hair loss, though further research is needed to determine its clinical applications.
February 2023 in “Medicine in novel technology and devices” This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.
July 2017 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers investigated the role of the ATX-LPA axis in asthma pathogenesis using human and mouse models and highlighted the potential for developing new ATX inhibitors as effective asthma treatments.
September 2024 in “Journal of the American Academy of Dermatology” In this case report, a 53-year-old woman with Little-Graham-Piccardi-Lassueur-Syndrome responded well to a treatment regimen of hydroxychloroquine, methotrexate, and other therapies, effectively halting the progression of this rare dermatosis characterized by alopecia and hyperkeratotic eruptions.
13 citations
,
February 2018 in “Bio-medical Materials and Engineering” This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.
1 citations
,
November 2024 in “Cutis” PLLA injections can cause hair loss and skin issues.
January 2024 in “Brazilian Journal of Hair Health” Combining low-level laser therapy with topical corticosteroids effectively improved Lichen Planopilaris symptoms.
44 citations
,
June 2017 in “The EMBO Journal” This study reports that the autotaxin–LPA–LPA3 signaling pathway at the embryo-epithelial boundary plays a critical role in decidualization by up-regulating HB-EGF and COX-2 in the uterine epithelium.
In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.
This case study reports that a 35-year-old woman developed nonscarring alopecia following the cosmetic use of poly-L-lactic acid on her face and hairline.
26 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the basics of hair follicle biology, laser/tissue interactions, and hirsutism and hypertrichosis causes, discussing the long-pulsed alexandrite laser's role in hair reduction without reporting new clinical results.
February 2026 in “Biomedicine & Pharmacotherapy” In this study, researchers developed EPO-derived peptides that enhanced hair growth by stimulating dermal papilla cells and increasing IGF-1 expression without triggering systemic erythropoietic effects in tested models, indicating a promising approach for treating hair loss.
13 citations
,
November 2022 in “Biomaterials Science” This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.
1 citations
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October 2023 in “BMC Genomics” This study identified miRNAs within the Dlk1-Gtl2 region on chromosome 18 as potential epigenetic regulators of lamb fur traits, with possible implications for the PI3K-AKT signaling pathway.
February 2019 in “Case medical research” Using lasers to deliver minoxidil can potentially improve its effectiveness in treating male pattern hair loss.
8 citations
,
June 2004 in “Journal of Investigative Dermatology” Certain peptides can prevent hair loss in young rats caused by a cancer drug.
1 citations
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January 2025 in “Proceedings of the National Academy of Sciences” This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.