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This review discusses the relationship between aging, chronic inflammation, and immunosuppression, suggesting that these interconnected processes may contribute to tumorigenesis and premature aging, but reports no new experimental results.

This review explores the potential impact of hormonal changes during aging on benign prostate hyperplasia-related urinary symptoms and metabolic syndrome, highlighting the hypothesis of a male PCOS-equivalent but reports no new clinical results.

This study found that DNA methylation changes in granulosa cells from PCOS patients affect gene expression related to insulin resistance, fat cell differentiation, and steroid metabolism, suggesting an epigenetic contribution to PCOS pathogenesis.

In this article, researchers link menopause to hair follicle lifecycle changes, noting that estrogen decline, metabolic shifts, genetics, and stress can contribute to hair thinning and texture variation, although effects differ among women.

This study found that bacterially induced metabolic changes in stem cells can enhance skin and hair follicle regeneration in both mice and humans, suggesting potential strategies for improving recovery after injury.

This review synthesizes both traditional and emerging molecular mechanisms of tissue remodeling across different organs, aiming to establish a theoretical basis for precision interventions in pathological conditions, according to the authors.

This review discusses how the hormonal changes of menopause affect skin and hair, highlighting improvements in skin symptoms like dryness and reduced wound healing with estrogen supplementation, and advises healthcare providers to consider broader potential benefits of menopausal hormone therapy when consulting patients.

Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.

In this study, the researchers identified CEP135 as a biomarker linked to poor sarcoma survival and suggested PLK1 as a potential therapeutic target for sarcoma patients with high CEP135 expression.

This review discusses the occurrence and impact of background histopathologic changes in nonhuman primate research, emphasizing the importance of understanding these factors to enhance study validity and interpretation.

Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.

This study observed that Nod factor stimulation in alfalfa roots leads to dynamic changes in the cytoskeleton and endoplasmic reticulum, suggesting a mechanism for root hair growth changes.

This study found that transgenic mice overexpressing the SSAT gene under a metallothionein promoter suffered delayed hair loss and were highly sensitive to polyamine analogues, which led to significant liver changes and mortality.

This review discusses the potential of repeated low-level red-light therapy to inhibit myopia progression through metabolic effects, highlighting its molecular and cellular impact, but reports no new clinical results.

This review discusses the complexity and varied symptoms of polycystic ovary syndrome and emphasizes lifestyle changes and insulin-sensitizing agents as effective management strategies, but reports no new clinical results.

This study found that in male mice, microglial changes due to a Parkinson's-like lesion were influenced by sex hormones, with dutasteride treatment preventing some effects.

This study observed that methylene blue, a mitochondrial-targeted antioxidant, promotes hair follicle stem cell proliferation and viability through reduced oxidative stress and enhanced β-catenin signaling, and it may also protect against hair loss related to glucagon-like peptide-1 receptor agonists by reducing metabolic stress.

This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This study found that in prodromal Alzheimer's disease, pro-inflammatory gut bacteria were associated with reduced cerebral blood flow and reactivity, while beneficial gut bacteria correlated with better outcomes.

In this study, researchers observed that follicular microinflammation significantly contributes to the early stages of male androgenetic alopecia, potentially leading to perifollicular fibrosis and follicle destruction as the condition progresses.

This study found that Polygonum multiflorum extract may promote hair growth by increasing anagen duration and activating dermal papilla cells in human hair follicles, as observed in cultured cell models.

This study reviews iron metabolism in the skin, highlighting how differentially expressed genes regulate iron recycling in the epidermis, and discusses changes in iron metabolism related to skin diseases.

In this study, around 1% of proteins in skin fibroblasts significantly changed in response to reductive stress, affecting collagens and MAPK signaling pathways.

In this study on mouse preputial glands, suppressing ATG7-dependent autophagy delayed age-related changes, affected lipid metabolism, and reduced pheromone production, highlighting autophagy's roles in glandular homeostasis and cell breakdown.

This study found that by using an automated system to analyze skin histology, 108 structural features were significantly affected by age, and it identified four new aging biomarkers and notable sex-based differences in skin aging.

This study found that the clionasterol-rich hexane fraction of Caulerpa racemosa may protect against particulate matter-induced skin damage by reducing oxidative stress and mitochondrial-mediated apoptosis in human keratinocytes and zebrafish.

This review discusses the biological and cosmetic aspects of hair aging and reports no new clinical results; it highlights current treatments and future research directions to address both aging factors.

This review discusses various weight loss treatment options for managing PCOS in women, including lifestyle changes, diet, medications, and surgery, but reports no new clinical results.

In this laboratory study, researchers observed that mouse vascular endothelial cells exhibit dynamic changes after exposure to ionizing radiation, including a transient endothelial subpopulation that facilitates vascular-epidermal communication and skin repair, with shifting roles in angiogenesis and immune surveillance over time.

This source provides medical information intended solely for licensed professionals and emphasizes that it is not a substitute for medical advice, diagnosis, or treatment decisions, which remain the responsibility of treating physicians.