8 citations
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August 2021 in “PubMed” This review found that oral spironolactone is an effective and well-tolerated treatment for androgenic alopecia in women, especially when used with topical minoxidil, with generally minimal side effects reported.
8 citations
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July 1983 in “Veterinary Quarterly” This study found that treating dermatomycosis in cats and dogs with ketoconazole for 20 days resulted in new hair growth and a high rate of clinical cure, with minimal side effects.
6 citations
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November 1999 in “Mycoses” This case study of a 75-year-old Japanese man with kerion Celsi found that terbinafine treatment was effective and safe, achieving a cure with minimal side effects.
5 citations
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April 1999 in “PubMed” This source notes that topical minoxidil and oral finasteride can modestly maintain or regrow hair in men with androgenic alopecia, especially at the scalp vertex, with minimal side effects.
2 citations
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January 2024 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” This case report highlights that a 25-year-old female with Alopecia Areata showed significant hair regrowth on bald patches after three months of combined internal and external Ayurvedic treatments, offering a potential alternative to conventional treatments with minimal side-effects.
2 citations
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September 2022 in “Bioscientia medicina” This literature review highlights the effectiveness of topical vitamin D (e.g., calcipotriol, calcitriol) in treating vitiligo, emphasizing its role in melanogenesis and as an immunomodulator, either alone or combined with topical corticosteroids, offering minimal side effects.
This study investigated the safety and efficacy of IV iron maltoside 1000 in treating iron-deficiency anemia among children with IBD and found a significant increase in hemoglobin levels by 6 weeks, maintained for up to a year, with minimal side effects reported.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study aims to develop and evaluate a trio pack of polyherbal hair care products—including shampoo, conditioner, and serum—with the goal of promoting hair and scalp health due to the benefits of herbal ingredients and minimal side effects.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlighted the potential benefits of herbal hair oils, detailing how formulations combining specific medicinal plants and carrier oils may promote hair health by stimulating hair follicles and reducing hair fall, as supported by preclinical and clinical studies with minimal side effects.
January 2026 in “Al-Azhar Assiut Medical Journal” In this study, intralesional pentoxifylline was found to be an effective and well-tolerated treatment for alopecia areata, showing significant improvements in hair loss with minimal side effects and a low recurrence rate among the 50 patients tested over 12 weeks.
December 2025 in “The International Journal of Medical Science and Health Research” This literature review explored the potential of Rosmarinus Officinalis as a plant-based solution for Androgenetic Alopecia, highlighting its effectiveness and minimal side effects compared to conventional treatments, which often have significant adverse effects.
November 2025 in “Dermatology Reports” This review found that microinfusion of medications using tattoo devices (MMP®) shows potential as a minimally invasive method for treating ailments like alopecia and basal cell carcinoma, offering notable improvements with minimal side effects due to localized drug delivery.
August 2025 in “Research Journal of Science and Technology” This review explores the historical and contemporary use of herbs in hair care, highlighting their advantages over synthetic alternatives, such as minimal side effects and environmental benefits, while calling for more scientific research to validate their efficacy.
July 2025 in “Phytomedicine Plus” This study reported that Cyperus rotundus L., a plant used in traditional medicine, effectively reduces hair growth with minimal side effects, showing efficacy comparable to Alexandrite laser treatments in certain cases, particularly for white hair, positioning it as a potential natural alternative to chemical depilatories.
July 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that platelet-rich plasma therapy significantly improved hair density and reduced hair shedding in Vietnamese patients with androgenetic alopecia, with high patient satisfaction and minimal side effects.
June 2025 in “International Journal of Science and Research (IJSR)” This study found that oral tofacitinib at a 5mg twice daily dosage was effective in treating recalcitrant alopecia areata, showing significant improvement in hair regrowth and a 27% reduction in SALT scores over six months, with minimal side effects among the 19 patients monitored.
May 2025 in “Dermatologie pro praxi” This study describes a new, minimally invasive method for treating androgenetic alopecia through autologous transplantation of progenitor cells, which may enhance hair follicle regeneration and delay disease progression with minimal side effects.
May 2025 in “International Ayurvedic Medical Journal” In this case report, a 19-year-old male with alopecia areata showed complete relief from symptoms and increased hair density after 90 days of Shamana therapy, suggesting its potential effectiveness in treating this condition with minimal side effects.
May 2025 in “Journal of Drug Delivery and Therapeutics” This review discusses the integration of modern and Unani medicine in the management of Benign Prostatic Hyperplasia, highlighting the potential of Unani herbal formulations as promising alternatives with minimal side effects but reports no new clinical results.
In this study, researchers formulated and evaluated herbal hair serums incorporating natural ingredients like flax seed, fenugreek, and castor oil, finding that the best formulation supported hair growth with minimal side effects compared to existing herbal serums.
January 2025 in “Lasers in Surgery and Medicine” This study found that combining fractional CO2 laser with topical minoxidil 5% solution significantly improved hair growth in alopecia areata patients compared to minoxidil alone, with minimal side effects.
January 2025 in “International Journal of Biological Innovations” This review article discusses the potential benefits of phytochemicals in hair care, highlighting their ability to improve scalp health, reduce dandruff, and promote hair growth, while emphasizing their safety and minimal side effects compared to conventional therapies.
This study found that injecting growth factor concentrates into the scalp of five patients with androgenic alopecia led to notable improvements in hair density and quality over eight weeks, with patients reporting satisfaction and minimal side effects.
June 2024 in “Lasers in Surgery and Medicine” This study found that the novel dermal cooling system was an effective and safe treatment for reducing pigmentation in benign pigmented lesions in Asian patients, with minimal side effects.
In this study, data from multiple sources found that Baricitinib significantly promoted hair regrowth and improved patient-reported outcomes in those with severe alopecia, with minimal side effects, over a 36-week period.
March 2024 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān/Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān./Zahedan journal of researches in medical sciences” This case study describes the successful treatment of facial pigmentation using microneedling combined with platelet-rich plasma, suggesting high effectiveness with minimal side effects in this application.
January 2024 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and tested a new herbal hair oil combining fenugreek and aloe vera, reporting enhanced hair growth, effective dandruff protection, and a glossy finish, outperforming a marketed product while having minimal side effects.
January 2024 in “Journal of Natural Remedies” This review reported that various herbs including cinnamon, fenugreek, and turmeric may effectively treat polycystic ovarian disorder with minimal side effects, suggesting potential for herbal therapies to target the disorder's root causes and improve overall health.
November 2023 in “International journal of biology, pharmacy and allied sciences” This source discusses various causes of hair loss, including conditions like alopecia areata and infections like ringworm, and notes that herbal formulations are gaining attention as potential treatments due to their minimal side effects compared to synthetic drugs.
November 2023 in “Journal of Cosmetic Dermatology” In this study, tofacitinib treatment significantly reduced hair loss on the head and body, as well as nail involvement, in patients with alopecia areata over 18 months, with minimal side effects reported.