The Role of Topical Vitamin D in Vitiligo: A Narrative Literature Review

    September 2022 in “ Bioscientia medicina ”
    Nopriyati, M. Akip Riyan Saputra, Izazi Hari Purwoko, Theresia L. Toruan
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    TLDR Topical vitamin D is effective in treating vitiligo with few side effects.
    Vitamin D is implicated in melanogenesis and has therapeutic applications in dermatology, particularly for conditions like vitiligo, which is characterized by skin depigmentation due to melanocyte destruction by T cells. Topical vitamin D, with minimal side effects, is used in vitiligo treatment and comes in various forms such as calcipotriol, calcitriol, tacalcitol, maxacalcitol, and hexafluoro-1,25 dihydroxyvitamin D3. These can be used as monotherapy or in combination with topical corticosteroids. The literature review discussed the effectiveness of topical vitamin D in vitiligo treatment, highlighting its role in melanogenesis and as an immunomodulator.
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