2 citations
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December 2024 in “International Journal of Pharmaceutics” In animal studies, this research found that minoxidil-loaded air-pocket microneedles improved hair loss treatment efficiency compared to topical application, while effectively sealing punctured skin openings.
55 citations
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March 1973 in “PubMed” Minoxidil is a new drug that lowers blood pressure.
September 2021 in “Mağallaẗ al-Muẖtar li-l-ʿulūm” This report describes a case of two sisters with kinky, tangled hair diagnosed using trichoscopic and microscopic methods; they were treated with topical minoxidil.
1 citations
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April 2024 in “Anais Brasileiros de Dermatologia”
April 2018 in “Journal of Investigative Dermatology” This study found that twice-daily application of 5% Minoxidil did not significantly impact hair growth in Sinclair minipigs over 27 days.
February 2024 in “Current Medicinal Chemistry” In this study, minoxidil nanoparticles significantly increased hair growth rate in C57BL/6 mice compared to traditional minoxidil, suggesting enhanced effectiveness and potential as a new formulation.
6 citations
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November 1990 in “DICP” This study found that rapidly administered intravenous cimetidine may cause a significant drop in blood pressure in critically ill patients, whereas ranitidine does not appear to have the same effect.
In this case report, a young female who unintentionally ingested topical minoxidil experienced severe circulatory shock and acute pulmonary edema, emphasizing the need for immediate treatment with fluid resuscitation and vasopressors.
23 citations
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January 2011 in “International Journal of Immunopathology and Pharmacology” In this small study, topical minoxidil 2% was associated with an increase in normal hair shaft production in patients with Monilethrix without any reported side effects.
January 2024 in “Современные проблемы науки и образования (Modern Problems of Science and Education)” Miliacin helps extend the hair growth phase in mice with hair loss.
This report describes a 7-year-old girl with monilethrix who showed significant improvement while on acitretin treatment, but symptoms returned after stopping the medication.
Minoxidil can cause hair growth as a side effect.
3 citations
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May 2019 in “Journal of Cosmetic Dermatology” This study found that a 12-week supplementation with MePL, a solution of miliacin encapsulated within polar lipids, significantly reduced hair density in the telogen phase and improved scalp dryness and hair brightness in women with telogen effluvium.
May 2024 in “Journal of biomaterials science. Polymer ed.” This study found that three-layer dissolving microneedles for delivering Minoxidil showed improved skin drug penetration and reduced irritation risk compared to traditional Minoxidil cream, suggesting a promising alternative for alopecia areata treatment.
12 citations
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February 2022 in “Acta Biomaterialia” In this study, researchers found that dissolving microneedles made with hyaluronic acid enhanced the effectiveness of minoxidil in reducing hair loss and promoting hair growth in alopecia-affected mice more effectively than topical minoxidil alone, while using only 10% of the drug amount.
September 2017 in “PubMed” In this case report, a Danish family with monilethrix showed varying symptoms, diagnosed via dermatoscopy, microscopy, and gene sequencing. The study highlights that while no cure exists, oral minoxidil shows promise in a single case, and reducing hair trauma remains key for management.
October 2019 in “UNESP Institutional Repository (São Paulo State University)” This study found that oral minoxidil 1 mg daily was as effective and safe as topical minoxidil 5% solution for treating female pattern hair loss over 24 weeks, but more likely to cause excessive hair growth elsewhere.
1 citations
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October 2017 in “Food Additives & Contaminants: Part A” This study identified a new minoxidil analogue called triaminodil in an illegal hair-growth supplement, but no data on its chemical, toxicological, or pharmacological properties are available yet.
May 2025 in “Pediatric Dermatology” This systematic review identified topical and oral minoxidil as the most effective treatments for monilethrix, but noted the varying efficacy of oral retinoids and other treatments.
December 2023 in “Annales Pharmaceutiques Françaises” This study concluded that Trilayer Dissolving Microneedles show promise in enhancing Minoxidil delivery for treating alopecia areata by improving its bioavailability and reducing side effects.
4 citations
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March 2020 in “Scientific Reports” This study reported that polymeric nanofibers containing minoxidil sulphate showed effective encapsulation and stability, with minimal concentration loss over six months, making them potentially ideal for delivering this unstable drug in a more visually appealing and easier-to-apply form.
1 citations
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January 2018 in “Eastern Journal Of Medicine” In this case report, a 9-year-old girl using topical minoxidil for alopecia experienced a 6-second asystole with syncope, suggesting careful cardiac monitoring may be needed for minoxidil users.
July 2026 in “Journal of Drug Delivery Science and Technology”
July 2024 in “Journal of Investigative Dermatology” Most women continued using oral minoxidil for hair loss despite mild to moderate side effects.
6 citations
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October 2011 in “Archives de pédiatrie” This case report describes a young girl who experienced vasoplegic shock and prolonged tachycardia after ingesting hair lotion containing minoxidil, highlighting the need for extended monitoring due to potential persistent hemodynamic issues.
22 citations
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January 1979 in “JAMA” Minoxidil can lower blood pressure effectively and safely in emergencies.
11 citations
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December 2015 in “Indian journal of dermatology, venereology, and leprology” Dermoscopy quickly and accurately diagnosed a rare hair disorder in a 12-year-old girl.
August 2022 in “Journal of The European Academy of Dermatology and Venereology”
53 citations
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August 2019 in “Journal of The American Academy of Dermatology” This study observed that low-dose oral minoxidil and topical minoxidil 5% solution both improved hair density in women with female-pattern hair loss, but oral minoxidil may offer advantages in reducing hair shedding.
1 citations
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July 2018 in “CMAJ. Canadian Medical Association journal” This case report describes a three-year-old girl with a two-year history of hair loss who was previously treated with selenium sulfide shampoo, with no family history of alopecia.