One-Touch Embeddable Microneedles for Hair Loss Treatment

December 2024 in “ International Journal of Pharmaceutics ”

Keum‐Yong Seong, Min Jae Kim, Hyeseon Lee, Sodam Kim, Semin Kim, Hoon‐Soo Kim, Eui‐Man Jung, Beum‐Soo An, Seung Yun Yang

embeddable microneedles minoxidil MXD-loaded MNs topical applications in vivo studies MNs Rogaine

TLDR Microneedles offer a painless, effective, and easy-to-use hair loss treatment.

The study presents a new, painless drug delivery system using embeddable microneedles (MNs) for hair loss treatment. These MNs have an air-pocket design that allows them to implant into the skin and release over 90% of the loaded minoxidil within 48 hours, while also sealing skin punctures to reduce infection risk. In vivo studies demonstrated that MXD-loaded MNs were more effective than topical applications, indicating a promising, minimally invasive, and potentially self-administered treatment option for hair loss.

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Research cited in this study

14 / 14 results

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1 citations , July 2023 in “Pharmaceutics”

New microneedles deliver drugs through the skin accurately and effectively.

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Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

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Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

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Hair loss in men treated best with early medication or transplant, new treatments researched.

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Minoxidil effectively treats severe hypertension, but watch for side effects.

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Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

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Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

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Minoxidil promotes hair growth in male pattern baldness.

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