Oral Minoxidil in the Treatment of Hypertensive Crisis

    January 1979 in “ JAMA ”
    Barry J. Wood, Janardana N. Sharma, Thomas T. Crouch
    Image of study
    TLDR Minoxidil can lower blood pressure effectively and safely in emergencies.
    This paper reports on a case study of a 15-year-old girl with malignant hypertension who failed to respond to high doses of sodium nitroprusside but had a rapid lowering of blood pressure following oral administration of minoxidil, an experimental vasodilator used principally for the control of chronic refractory hypertension. The study suggests that minoxidil may be a safe and effective alternative to parenteral drug therapy for the treatment of malignant hypertension. The paper also notes that undesirable side effects of minoxidil, such as increased facial hair and fluid retention, can be averted by attempting to convert rapidly to conventional therapy once blood pressure is controlled.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community What's "wrong" with oral minoxidil, exactly?

      in Minoxidil  173 upvotes 1 month ago
      Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

      community Topical Minoxidil is a pain in the ass for diffuse thinners

      in Minoxidil  95 upvotes 1 year ago
      Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

      community Any long term diffuse thinners success stories?

      in Chat  27 upvotes 1 year ago
      A user with early-stage diffuse hair thinning asked for long-term success stories using treatments like finasteride, minoxidil, and RU58841. One person regained most of their hair after 22 months on finasteride and minoxidil, while another saw significant improvement with oral minoxidil after trying various treatments over many years.

      community Nizoral doesn't seem to be working. Rogaine not suggested by doctor due to cost and poor track record on females. Ideas?

      in Ketoconazole  22 upvotes 6 years ago
      A woman experiencing hair loss and facial hair growth suspects PCOS or androgenic alopecia and is considering treatments like Rogaine, but is concerned about the cost. She has tried various hair care methods and is awaiting a hormone doctor appointment, while others suggest she may have a hormonal imbalance and recommend seeing a gynecologist or trying cheaper versions of Rogaine.

    Related Research

    4 / 4 results