May 2026 in “Frontiers in Cell and Developmental Biology” In this study, researchers suggest that hair follicle miniaturization in conditions like androgenetic alopecia may result from impaired conversion of quiescent stem cells to progenitor cells, influenced by the follicular niche, its collagen network, and various mechanical constraints.
26 citations
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May 2015 in “Lasers in Surgery and Medicine” This study concluded that ablative fractional lasers may induce hair regrowth in mice by activating the Wnt/β-catenin pathway.
4 citations
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December 2020 in “Journal of Dermatology” This study suggests that impaired autophagy may be a potential mechanism contributing to androgenetic alopecia, as observed in miniaturized hair follicles from balding scalps.
January 2024 in “Wiadomości Lekarskie” This presentation explores burnout and compassion fatigue among healthcare professionals, detailing their causes, symptoms, and consequences, and emphasizes strategies for prevention and management, such as mindfulness and organizational support, to improve both provider and patient outcomes.
September 2017 in “Journal of Investigative Dermatology” This study found that dermal papilla cells exhibit stage-dependent variation in histone methylation during the hair follicle cycle and display distinct chromatin marker expression when transitioning to in vitro culture.
49 citations
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October 2017 in “Nutrients” This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
7 citations
,
September 2014 in “European Journal of Dermatology” This study found a significant positive correlation between hair thickness and growth rate, with a notably slower growth rate observed in men with male pattern hair loss compared to healthy controls.
27 citations
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February 2017 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a topical formulation with compounds from the monoterpenoid family significantly improved hair growth indicators like anagen:telogen ratio, hair fall, and visual hair density in men and women with pattern hair loss.
21 citations
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July 2014 in “British Journal of Dermatology” In this study, hair loss in Japanese men with androgenetic alopecia was found to be primarily due to hair follicle miniaturization rather than hair shedding, particularly in those aged 25 and older.
9 citations
,
January 2010 in “International Journal of Trichology” This study found that in Alopecia Areata, increased non-anagen terminal follicles and peribulbar lymphocytic infiltrate are consistent histological features, even in cases that have progressed to scarring.
229 citations
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August 2002 in “Experimental Gerontology” This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.
35 citations
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March 2014 in “British Journal of Dermatology” This study found that in androgenic alopecia, the arrector pili muscle degenerates and is replaced by fat, unlike in normal skin or telogen effluvium.
July 2008 in “Expert Review of Dermatology” This review discusses common mistakes in follicular unit transplantation and provides guidance for practitioners to enhance patient outcomes, but reports no new clinical results.
66 citations
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June 2018 in “International Journal of Women's Dermatology” This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.
30 citations
,
April 2009 in “Dermatologic Surgery” This study found that miniaturization of hair is present in some women with androgenetic alopecia, but diagnosis may also be based on differences in hair shaft diameter between scalp regions.
12 citations
,
January 2005 in “Journal of Cosmetic Dermatology” This review discusses the natural progression of androgenetic alopecia and potential factors influencing its long-term prognosis, reporting no new clinical results.
9 citations
,
June 2014 in “British Journal of Dermatology” The study found that balding scalps have more thin hairs and larger oil glands, which might contribute to skin conditions related to hair loss.
November 1999 in “Journal of Cutaneous Medicine and Surgery” Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.
19 citations
,
April 2020 in “Dermatologic Therapy” This review found that dutasteride is more potent than finasteride as a dual receptor dihydrotestosterone blocker for treating androgenetic alopecia and shares a similar safety profile in terms of fertility, teratogenicity, neurotoxicity, and hepatotoxicity.
90 citations
,
June 2006 in “The American Journal of Dermatopathology” This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.
30 citations
,
September 2017 in “Clinics in Dermatology” This review explores the relationship between androgenetic alopecia and metabolic syndrome, suggesting an association that supports considering cardiovascular risk assessments in patients with this type of hair loss.
29 citations
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March 2001 in “Clinics in Dermatology” This article discusses various types of primary cicatricial alopecias and reports no new clinical results; it emphasizes the importance of accurate diagnosis for effective management.
17 citations
,
September 2012 in “Dermatologic Clinics” This review discusses histologic findings in alopecia and emphasizes the importance of understanding normal follicular anatomy and cycles in transverse sections, without reporting new results.
12 citations
,
May 2016 in “British Journal of Dermatology” This article reviews androgenetic alopecia and its underlying mechanisms, highlighting genetic and androgen factors in its onset, and does not report new research results.
12 citations
,
November 2014 in “PLOS Computational Biology” In this study, researchers found that synchronization between expanding epithelial cells and background mesenchymal cells in the mouse hair cycle may be maintained by inhibitory regulation, with potential mediators of this regulation identified.
10 citations
,
June 1998 in “International Journal of Dermatology” This article discusses inflammatory perifollicular fibrosis and alopecia but provides no new research findings.
Dutasteride can stabilize hair loss in patients with frontal fibrosing alopecia, but its safety in women is unclear, so use it with caution.
4 citations
,
October 2018 in “Experimental Dermatology” This study suggests that diffuse alopecia areata initially involves an intense inflammatory attack during the anagen phase, progressing through different hair cycle stages with specific shedding patterns.
4 citations
,
April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
3 citations
,
January 2018 in “Dermatology” This study found that transverse sections of scalp biopsies, particularly looking at the anagen:non-anagen hair ratio and presence of pigment casts, effectively distinguish alopecia areata from androgenetic alopecia.