1 citations
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March 2009 in “Hair transplant forum international” This article reviews optimal patient selection and donor site quality for successful hair transplant procedures, but reports no new clinical findings.
57 citations
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February 2014 in “Experimental Dermatology” This review discusses the role of Prostaglandin D2 and its synthase in androgenetic alopecia but reports no new clinical findings, suggesting pathways for future therapeutic development.
40 citations
,
December 2006 in “Journal of The European Academy of Dermatology and Venereology” This article reports two cases where 2% topical minoxidil showed promise in treating traction alopecia, but it does not offer broader clinical conclusions.
28 citations
,
June 2000 in “PubMed” This article reviews the molecular mechanisms involved in androgenetic alopecia, focusing on the role of type 2 5α-reductase and DHT, but presents no new findings.
15 citations
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May 2002 in “PubMed” This article explores the hormonal and genetic factors influencing androgenetic alopecia and identifies potential targets for treatment but reports no new clinical findings.
1 citations
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July 2020 in “Revista Cereus” This study highlights microneedling as a safe and effective technique for treating androgenetic alopecia in men by permeating active agents, stimulating collagen, and enhancing angiogenesis, which may improve hair growth by activating cellular division and growth.
1 citations
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January 2012 in “Human health handbooks” This article reviews androgenetic alopecia and its genetic and hormonal influences, treatment options like minoxidil and finasteride, and its potential associations with other health conditions, reporting no new clinical results.
July 2026 in “Preprints.org” This review outlines the optimization of platelet concentrates for hair loss treatment and suggests extracellular vesicles as a key future element, aiming to advance point-of-care regenerative therapies despite the need for a unified framework and further research on underlying mechanisms.
This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.
May 2025 in “Frontiers in Bioengineering and Biotechnology” In this study, the researchers reported that a novel exosome-based treatment, EX104, effectively reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, showing results comparable to minoxidil and surpassing it in stimulating capillary growth and follicular proliferation.
September 2024 in “Revista Científica de Salud BIOSANA” This systematic review explored the potential of cetirizine, an anti-inflammatory antihistamine, as a complementary treatment for androgenetic alopecia, reporting that it might help prevent hair follicle miniaturization by reducing inflammation and modulating immune activity, without notable side effects.
April 2023 in “Journal of Investigative Dermatology” This study explores how chromatin differences between dermal papilla cells and papillary fibroblasts contribute to hair follicle inductivity and investigates the regulatory changes in androgenic alopecia.
Hair loss in women can be caused by genetics, menopause, certain health conditions, and emotional stress, and it often results in thinner hair and a changing hairline.
224 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” This article discusses the hair follicle's regenerative cycles and the molecular mechanisms influencing them, emphasizing the need for therapeutic targeting of the "hair cycle clock" to manage hair growth disorders, without reporting new research findings.
8 citations
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April 2017 in “Journal of Dermatological Science” The study found that aging in hair follicle stem cells leads to hair follicle miniaturization and eventual hair loss in both wild-type mice and humans by proteolyzing type XVII collagen.
February 2026 in “Nature Communications” This study combined spatial and single-cell transcriptomics to identify that hypercontractility of the connective tissue sheath activates PIEZO1 in hair follicles, leading to miniaturization in male androgenetic alopecia, and found that inhibiting this contraction improves hair growth in models.
July 2021 in “British Journal of Dermatology” This case report describes a novel instance of scarring alopecia with features of frontal fibrosing alopecia in a patient with systemic sclerosis, suggesting a potential link between the two conditions not previously reported.
July 2025 in “The FASEB Journal” This study reported that exosomes derived from human amniotic mesenchymal stem cells (hAMSC-exo) accelerated hair growth in androgenetic alopecia mice by enhancing signals between hair follicle cells and improving cellular environments, particularly protecting against dihydrotestosterone-induced damage via Wnt/β-catenin signaling.
September 2017 in “Journal of Investigative Dermatology” Loss of COL17A1 causes hair follicle stem cells to age and leads to hair loss.
January 2002 in “Hair transplant forum international” This article explores the effects of DHT on hair follicle miniaturization and finasteride's role in preventing this process, without presenting new clinical data.
August 2016 in “Journal of Investigative Dermatology” This study found that dihydrotestosterone alters the balance of Wnt pathway regulators in dermal papilla cells, hindering hair follicle stem cell differentiation and contributing to hair follicle miniaturization.
4 citations
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June 2017 in “Anais Brasileiros De Dermatologia” This study demonstrates that miniaturized hair follicles in female pattern hair loss overexpress nuclear aryl hydrocarbon receptors, suggesting a potential role for environmental pollutants in this condition.
June 2024 in “Computational and Structural Biotechnology Journal” This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.
116 citations
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September 2001 in “Journal of The American Academy of Dermatology” This study suggests that miniaturization in pattern hair loss may occur abruptly and can be reversed with treatment, as supported by histologic evidence in finasteride-responsive patients.
9 citations
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June 2017 in “Journal of Cutaneous Pathology” This study found that follicular acantholysis is a common histopathological feature in pemphigus, with differences in depth between pemphigus vulgaris and pemphigus foliaceus lesions that may aid in diagnosis.
145 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.
1 citations
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May 2019 in “Journal of The European Academy of Dermatology and Venereology” New method, hair distribution width (HDW), improves accuracy in diagnosing androgenetic alopecia (AGA).
May 2025 in “LUMEN ET VIRTUS” This study reports that perioperative nursing care for hair transplant patients improves outcomes by reducing complications and enhancing patient satisfaction, emphasizing the crucial role of nurses in managing the procedure.
August 2024 in “Journal of Contemporary Medical Practice” In this analysis, Professor Ma Shuanquan attributes androgenetic alopecia to liver, spleen, and kidney dysfunctions and describes a treatment approach using Chinese medicines focused on these organs, suggesting individualization and noting significant therapeutic effects.
8 citations
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June 2019 in “Scientific Reports” This study found that the retinoid receptor and PPAR pathway are involved in hair follicle miniaturization in androgenetic alopecia, alongside androgen receptors.