Sequential Cyclic Changes of Hair Roots Revealed by Dermoscopy Demonstrate a Progressive Mechanism of Diffuse Alopecia Areata Over Time

    October 2018 in “ Experimental Dermatology ”
    Xingqi Zhang, Yanting Ye, Zhen Zhu … Yunxia Ling
    Studysummary This study suggests that diffuse alopecia areata initially involves an intense inflammatory attack during the anagen phase, progressing through different hair cycle stages with specific shedding patterns.
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    Research cited in this study 20

    1. Female Pattern Alopecia and Telogen Effluvium: Figuring Out Diffuse Alopecia Seminars in Cutaneous Medicine and Surgery · 2015
    2. Scalp Dermoscopy or Trichoscopy Current problems in dermatology · 2015
    3. Morphological Changes of the Hair Roots in Alopecia Areata: A Scanning Electron Microscopic Study Journal of Dermatology · 2013
    4. Early Stage Alopecia Areata Is Associated With Inflammation in the Upper Dermis and Damage to the Hair Follicle Infundibulum Australasian Journal of Dermatology · 2013
    5. Anagen Effluvium: A Review of Rapid Hair Loss During Growth Phase and Loose Anagen Hair Syndrome Indian Journal of Dermatology, Venereology and Leprology · 2013
    6. Histopathologic Features of Alopecia Areata Incognito: A Review of 46 Cases Journal of Cutaneous Pathology · 2012
    7. Diffuse Alopecia Areata Is Associated With Intense Inflammatory Infiltration and CD8+ T Cells in Hair Loss Regions and an Increase in Serum IgE Level Indian Journal of Dermatology, Venereology and Leprology · 2012
    8. Alopecia Areata Incognita: A Comment Clinics · 2011
    9. Investigative Guidelines for Alopecia Areata Dermatologic therapy · 2011
    10. Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician? Dermatologic Therapy · 2011
    11. Alopecia Areata Incognita: A Case Report Clinics · 2011
    12. The Cell Biology of Human Hair Follicle Pigmentation Pigment cell & melanoma research · 2010
    13. Patients With Profuse Hair Shedding May Reveal Anagen Hair Dystrophy: A Diagnostic Clue of Alopecia Areata Incognita Journal of the European Academy of Dermatology and Venereology · 2010
    14. Alopecia Areata Incognita: A Hypothesis Dermatology · 2009
    15. The Role of Scalp Dermoscopy in the Diagnosis of Alopecia Areata Incognita Journal of The American Academy of Dermatology · 2008
    16. Significance of Dermoscopy in Acute Diffuse and Total Alopecia of the Female Scalp: Review of Twenty Cases Dermatology · 2008
    17. Acute Diffuse and Total Alopecia of the Female Scalp: A New Subtype of Diffuse Alopecia Areata That Has a Favorable Prognosis – A Reply Dermatology · 2003
    18. Acute Diffuse and Total Alopecia of the Female Scalp Dermatology · 2002
    19. Melanocyte and Gonad Activity as Potential Severity Modifying Factors in C3H/HeJ Mouse Alopecia Areata Experimental dermatology · 2001
    20. Telogen Effluvium: A Comprehensive Review Archives of Dermatology · 1993

    Related research 6

    1. Use of Trichoscopy for the Diagnosis of Alopecia Areata Coexisting with Primary Scarring Alopecia in a Female Hair Loss Patient Journal of Dermatology · 2019
    2. Hair Disorders Oxford University Press eBooks · 2018
    3. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    4. Standardization of Trichotillometer 2009
    5. Female-Patterned Alopecia in Teenage Brothers with Unusual Histologic Features Journal of Cutaneous Pathology · 2006
    6. Diseases of the Hair and Scalp Medical Entomology and Zoology · 1991