88 citations
,
May 2005 in “Journal of Dermatological Science”
In this study, specific versican expression was observed in the anagen phase of human hair follicles, suggesting its importance in maintaining normal hair growth.
29 citations
,
July 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”
This study observed that in mouse hair follicles, enzymes Aldh1a2 and Aldh1a3 have distinct expression patterns that suggest they are involved in different signaling pathways during the haircycle.
32 citations
,
February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”
This study reports the cloning and sequencing of two type II hair-specific keratin genes, ghHb1 and ghHb6, located on chromosome 12q13, which are expressed during hair growth.
This study examined gene expression in cashmere goats and identified key pathways and molecular regulators that influence hair follicle growth stages and melatonin's role in promoting cashmere growth.
The conversation discusses hair loss treatments, specifically using finasteride, dutasteride, RU58841, and minoxidil. Users share experiences on maintaining or regrowing hair during testosterone cycles.
Hair regrowth from treatments like finasteride, dutasteride, and minoxidil can take several years, with most visible results appearing within 1-2 years and potential improvements continuing up to 10 years. Consistency and patience are crucial for achieving maximum hair thickness, as hair miniaturization and regrowth are gradual processes.
The conversation discusses hair loss treatments, specifically finasteride, for a 21-year-old FTM individual concerned about hairline recession. Users suggest finasteride and possibly topical minoxidil, while noting potential side effects like menstrual cycle return and brain fog.
The conversation discusses hair loss treatments, specifically finasteride, minoxidil, ketoconazole shampoo, and microneedling, with users experiencing initial success followed by increased shedding and regression. Many users suggest patience, as haircycles can take years, and some attribute changes to seasonal shedding.
Poor sleep quality may affect hair growth cycles by disrupting the body's natural clock and stress hormones. The focus should be on improving sleep to support overall health, including hair growth, rather than relying solely on treatments like Minoxidil, finasteride, or RU58841.
mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth
Is rapamycin safe for long-term use on the scalp, or should it be used in cycles?There is no published human trial of topical rapamycin on the scalp, so nobody knows whether long-term use is safe; the idea of cycling it comes from community practice and theory, not from any study or guideline, and rapamycin for hair loss is an off-label use of a prescription immunosuppressant.
How long does it take for cyproterone to work on hair loss?There is no reliable published figure for how fast cyproterone works on hair loss: the hair cycle means nothing shows for months, the one randomised trial assessed women at twelve months, and community reports range from about six months to two years — with some people seeing no change at all.