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Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

Hair analysis can help diagnose adrenal disorders non-invasively.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

People with common hair loss conditions may have a higher risk of heart disease and related health issues.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Blocking LFA-1 prevents hair loss in mice.

People with early-onset hair loss (AGA) have a higher risk of heart disease, metabolic syndrome, and prostate enlargement.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Licorice has many health benefits but should be used carefully due to possible side effects.

A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

The birth control combination of ethinylestradiol and drospirenone helps treat symptoms of polycystic ovary syndrome.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Early balding in young Indian men may indicate a higher risk of metabolic syndrome and potential heart disease.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Metabolic syndrome is more common in people with early-onset androgenic alopecia.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Men with early-onset hair loss have more heart disease risk factors.

The glucocorticoid receptor helps protect skin from tumors and other issues.

Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.