Comorbidities in Patients with Androgenetic Alopecia: Cardiovascular Risk Factors and Benign Prostatic Hyperplasia
July 2011
TLDR People with early-onset hair loss (AGA) have a higher risk of heart disease, metabolic syndrome, and prostate enlargement.
This study aimed to analyze the relationship between androgenetic alopecia (AGA) and cardiovascular risk factors, as well as the association between AGA and benign prostatic hyperplasia (BPH). The study included 300 participants with AGA and healthy control subjects. The results showed that metabolic syndrome and atheroma plaque were more prevalent in individuals with AGA. AGA patients also had higher intima-media thickness and a higher prevalence of hypertension, abdominal obesity, dyslipidemia, and diabetes. Additionally, AGA was found to be an independent risk factor for metabolic syndrome and atheroma plaque. In male AGA patients, there was a higher mean prostate volume and urinary symptoms associated with prostate growth. The study suggests that early-onset AGA may serve as an early marker for urinary/prostatic symptomatology. Screening methods such as determining metabolic syndrome, ultrasound study of the carotid arteries, and assessing urinary prostatic symptoms may be useful in detecting the risk of developing cardiovascular disease or BPH in patients with early-onset AGA.