Male Androgenetic Alopecia and Cardiovascular Risk Factors

January 2015

A Case-Control

androgenetic alopecia metabolic syndrome carotid atherosclerosis atheromatous plaques cardiovascular screening male pattern baldness heart disease screening

TLDR Men with male pattern baldness are more likely to have heart disease risk factors, so they should get heart screenings early.

The study conducted in 2014 involved 70 male participants, 35 with male androgenetic alopecia and 35 controls, aged between 35 to 55 years. The research aimed to determine the prevalence of metabolic syndrome and carotid atherosclerosis in male patients with androgenetic alopecia. The results showed that 57.1% of patients with androgenetic alopecia met the criteria for metabolic syndrome compared to 14.3% of the control group. Additionally, 34% of patients with androgenetic alopecia had atheromatous plaques compared to 8.6% of the controls. The study concluded that due to the high frequency of metabolic syndrome and carotid atheromatous plaques in patients with androgenetic alopecia, cardiovascular screening should be conducted for early detection and initiation of preventive treatment before cardiovascular disease becomes established.

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Research cited in this study

6 / 6 results

research Elevated Aldosterone Levels in Patients with Androgenetic Alopecia

30 citations , November 2009 in “British Journal of Dermatology”

Higher aldosterone levels link to hair loss and high blood pressure.

research Is Androgenetic Alopecia a Risk for Atherosclerosis?

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Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia

research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia

67 citations , August 2007 in “American Journal of Pathology”

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

research Association of Androgenetic Alopecia and Hypertension

34 citations , May 2007 in “PubMed”

Balding in men is strongly linked to high blood pressure and family history.

research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study

56 citations , June 2001 in “European journal of cardiovascular prevention & rehabilitation”

Early balding linked to higher heart disease risk.

research Early Androgenetic Alopecia as a Marker of Insulin Resistance

115 citations , September 2000 in “The Lancet”

Early hair loss may indicate risk of insulin resistance.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

in Research/Science 27 upvotes 3 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Do we have to be junkies? That's funny

in Research/Science 13 upvotes 1 year ago

The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

community How much do you guys think diet and sleep affects results?

in Research/Science 36 upvotes 2 years ago

The conversation discusses whether lifestyle factors like diet and sleep affect hair growth in people with reversible hair loss. Some believe these factors, along with treatments like minoxidil, finasteride, and RU58841, can improve hair health, while others argue hair loss is mostly determined by genetics and DHT sensitivity.

community Dutasteride Infertility Debunked: Low T causes true infertility.

in Finasteride/Dutasteride 166 upvotes 7 months ago

Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.

community Update on my progress after 10,5 months

in Progress Pictures 149 upvotes 9 months ago

The user has been using a combination of oral finasteride, oral dutasteride, topical and oral minoxidil, microneedling, and keto shampoo for hair loss, experiencing significant shedding recently. Suggestions include simplifying the regimen by dropping finasteride and topical minoxidil, and possibly adding RU58841, while others advise maintaining the current approach for consistent results.

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