Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, blocking autophagy with 3-methyladenine significantly improved the survival of inner ear hair cells in a gentamicin-induced ototoxic mouse model.

This communication reports previously unreported side effects, severe bullous dermatosis and onycholysis, in three patients undergoing high-dose methotrexate and leucovorin calcium therapy, impacting their chemotherapy schedules.

This report describes two cases of Majocchi's granuloma in immunocompromised patients, highlighting the importance of considering this condition in such populations.

This communication discusses previous reports of deadly hematopoietic depression associated with the topical use of demecolcine for skin cancers, highlighting potential hazards relative to colchicine ointment in psoriasis.

In this study, Pleuropterus cilinervis extracts and animal milk fermented with Lactobacillus rhamnosus were found to enhance hair re-growth in mice more than the positive control treatment.

This case study describes successful treatment of a siamang's persistent Microsporum canis infection using a sustained-release clotrimazole varnish, leading to lesion resolution after two years of clinical signs.

This study investigated the modes of action of selected pesticides, suggesting that prochloraz and tebuconazole are linked to reproductive disorders via steroidogenesis disruption, while mancozeb involves inflammatory processes.

This review reports that the compound Cepharanthine shows promise as a cancer therapy by inducing cell death, arresting cell growth, inhibiting tumor progression, modulating key oncogenic pathways, and reversing multidrug resistance, suggesting its potential for further investigation in oncology.

This study reports that retinol acetate inhibited the pro-oxidant effects of benoxaprofen on polymorphonuclear leucocytes in vitro.

This review found that tea tree oil, especially terpinen-4-ol, may be the most effective treatment for Demodex-related diseases, but more research is needed to improve treatment efficacy and reduce side effects.

This study found that early diagnosis using gas chromatography/mass spectrometry and appropriate long-term treatment are crucial for improving outcomes in patients with methylmalonic acidemia.

In this study, a five-year-old Labrador with pemphigus, characterized by erythematous lesions and confirmed through cytology, was successfully treated with a six-week regimen of oral immunosuppressive azathioprine and supportive medications, resulting in total recovery.

This study reported a 74% overall response rate for a new combination chemotherapy of mitoxantrone, etoposide, and prednisolone in patients with relapsed or refractory Hodgkin's disease or non-Hodgkin's lymphoma.

This study reported that while general patient characteristics and adverse event incidence for eribulin were comparable between a healthcare claims database and post-marketing surveillance, significant differences in some side effects such as neutropenia were observed.

This study found that a combination of ciclosporin and Miglyol 812 was effective in treating sebaceous adenitis in rabbits, with significant improvement in skin condition and hair regrowth.

This study found that pimecrolimus enhances melanin synthesis and promotes melanocyte migration, possibly by increasing MITF protein expression, which may explain its effectiveness in repigmenting vitiligo.

This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.

This study used molecular docking simulations to identify Adapalene, Diosmin, and Azelastine as promising drugs for repurposing against onchocerciasis by targeting proteins in the parasite and its endosymbiont; further research is needed to confirm their efficacy.

This study found that a 12-week supplementation with MePL, a solution of miliacin encapsulated within polar lipids, significantly reduced hair density in the telogen phase and improved scalp dryness and hair brightness in women with telogen effluvium.

In this case report, a 2-month-old Chippiparai pup in Puducherry, India, successfully received treatment for concurrent scabies and dermatophytosis using ivermectin, a topical acaricide solution, a dewormer, and an herbal immunostimulant, with no signs of toxicity.

In this study involving a murine skin infection model, researchers found that the Trichophyton mentagrophytes strain TIMM 2789, specific to rodents, induced typical symptoms of superficial dermatophytosis, while revealing that the fungal gene SUB6 is not essential for virulence.

This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.

This case study reports the first clinical case of besnoitiosis in two donkeys in Italy, suggesting a wider distribution of the disease in European equids than previously expected.

This study reported that 39.7% of Amargosa voles had mite-associated lesions, which may severely impact their health and fitness.

This study found that topical application of bovine milk polar lipids accelerated hair cycle progression in mice, showing potential for use in cosmetic products.

This phase Ib study found that combining pegylated liposomal doxorubicin and pembrolizumab was well-tolerated and effective, with durable antitumor responses and a median survival of over two years in heavily pretreated ER-positive metastatic breast cancer patients.

This study found that Adapalene, Diosmin, and Azelastine have potential as multi-target drugs against Onchocerca volvulus and its endosymbiont, which might offer new therapeutic options for treating river blindness, but further research is needed to confirm their effectiveness.

In this study, wounds treated with a combination of 0.02% Decamethoxine and Blastomunil showed enhanced healing and epithelization by the 14th day, leveraging the immunomodulatory and antimicrobial properties of the agents.

This chapter discusses the synthesis and analysis of near-infrared fluorescent activity-based probes for imaging cysteine protease activity, reporting potential benefits for disease diagnosis but noting challenges in imaging specific locations with high cathepsin activity.

In this case study, gentian violet in diluted shampoo successfully alleviated symptoms of a Malassezia pachydermatis infection in a cat initially unresponsive to conventional treatments.