New-Onset Majocchi’s Granuloma in Two Kidney Transplant Recipients Under Tacrolimus Treatment

    Mario Sequeira, Anne E. Burdick, George W. Elgart, Brian Berman
    TLDR Majocchi's granuloma can occur in kidney transplant patients on tacrolimus and can be treated with antifungal medication.
    The document described two cases of Majocchi's granuloma in kidney transplant recipients under tacrolimus treatment, highlighting its rarity in such patients. Both cases involved skin lesions that resolved with antifungal treatments, specifically terbinafine and itraconazole. The study emphasized that while tacrolimus is typically associated with bacterial or viral infections, Majocchi's granuloma should be considered by dermatologists as a potential diagnosis in immunosuppressed patients. A previous study indicated a 12% incidence of dermatophyte infection among 200 patients on various immunosuppressants, underscoring the importance of recognizing and treating this condition.
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