Optimization of a Murine Infection Model With Trichophyton Mentagrophytes for Studying the Pathogenesis of Dermatophytosis

This study found that terbinafine prevented the invasion of keratin by Trichophyton mentagrophytes in experimental models replicating human dermatomycoses.

In this study, an infection model using rabbits was developed for dermatophytosis by inoculating macroconidia of Microsporum species, showing that direct intradermal application effectively progressed to the skin invasion phase and highlighted the correlation between severity of symptoms and duration post-inoculation.

This study found that human hair shows more susceptibility to perforation by Trichophyton mentagrophytes and Trichophyton verrucosum compared to animal hair, with black human hair serving as a reliable diagnostic tool for differentiation between the two species.

This study observed an outbreak of dermatophytosis caused by Trichophyton species in farmed mink in the USA, affecting primarily dark-colored kits with skin lesions.

This study found that in mice, Bacillus anthracis infections destroy hair follicles by progressing inward from the surface and clear when inflammatory cells disperse the bacteria after 3-4 days.