Use of a Sustained Release Preparation of Clotrimazole to Treat Dermatophytosis in a Siamang (Hylobates Syndactylus)

    March 2008 in “ Journal of Zoo and Wildlife Medicine ”
    Nili Avni‐Magen, D. Elad, Michael Friedman, Irith Gati, Elizabeth Kaufman, Eran Lavy
    TLDR A special clotrimazole varnish cured a siamang's persistent skin infection after 3 months.
    In November 2004, an adult male siamang at The Tisch Family Zoological Gardens in Israel was diagnosed with dermatophytosis caused by Microsporum canis, presenting with alopecia and hyperkeratosis. Initial treatments with oral and topical antifungal agents resolved most lesions, but one persisted. An experimental sustained-release clotrimazole varnish was applied directly to the lesion under anesthesia. After an initial lack of response, a modified formula was used, leading to a reduction in lesion size one month later. The lesion fully resolved three months after treatment began, highlighting the benefit of minimizing treatment frequency in exotic animals.
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      community Should I start minoxidil before finasteride?

      in Treatment  3 upvotes 2 years ago
      A 21-year-old male from Bangladesh is experiencing hair loss and was advised by a dermatologist to use ketoconazole shampoo, anti-fungal treatments, biotin, and 5% minoxidil, with finasteride to be considered after six months. The user is unsure whether to follow this advice or start finasteride immediately alongside minoxidil.

      community Hair is kinking rapidly following hair loss

      in Update  1 upvotes 8 months ago
      Hair loss has slowed, but uneven growth and kinking persist despite using keto/nizoral shampoo and clotrimazole. Stress and anxiety might be contributing factors.

      community Will stopping ketoconazole make a difference?

      in Ketoconazole  11 upvotes 1 year ago
      The user has been using finasteride and ketoconazole for hair loss and is considering changing shampoos due to dryness caused by ketoconazole. Responses suggest that stopping ketoconazole won't affect hair loss unless the user has seborrheic dermatitis, and recommend using conditioner or using ketoconazole shampoo less frequently.

      community No effect Over 6 months, am I doing this wrong?

      in Update  3 upvotes 8 months ago
      The user experienced no improvement in hair loss after using a dermatologist's minoxidil 10% and finasteride 0.1% solution, clotrimazole, daily dermarolling, and multivitamins. They plan to switch to oral finasteride and reduce dermarolling to once a week.

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