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This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.

In this study, the 40-MBR system was shown to enhance drug-screening efficiency by providing reliable, real-time monitoring of cell conditions in 3-D cultures compared to traditional methods.

This study introduced laser particles as a new imaging probe capable of real-time tracking of thousands of individual cells in 3D tumor models, suggesting potential for advanced single-cell analyses.

This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.

This study reports the development of a fluorescent ionic liquid that shows high sensitivity and selectivity for detecting dextran sulfate sodium, with potential applications in clinical diagnostics and environmental monitoring.

This study introduces a customizable 3D-printed microscope stage insert for inverted confocal microscopes, improving accessibility and usability of intravital microscopy for observing cell dynamics in live mice.

This study introduced a high-viscosity epoxy photoresist to enhance the fabrication of complex microstructures with monolithic integration and mechanical stability, enabling advancements in two-photon 3D printing for creating functional micro-mechanical devices.

This study successfully isolated inner ear-specific exosomes from perilymph samples of sensorineural hearing loss patients using a novel immunomagnetic approach, enabling groundbreaking liquid biopsy diagnostics.

This study demonstrates that a 3D-printed agarose microwell platform supports the growth of size-uniform, viable NSCLC cancer spheroids, and can effectively evaluate drug responses using limited tumor material from biopsies, particularly with EGFR tyrosine kinase inhibitors gefitinib and osimertinib.

This study presented a new method for accurately measuring Fe³⁺ in small serum samples, achieving high recovery rates and agreement with established testing methods, while offering advantages such as cost-effectiveness, simplicity, and enhanced sensitivity.

This study introduced a novel in vitro murine assay using transgenic mice to identify immunomodulatory compounds, which identified 160 potential hits from 4,398 compounds screened.

In this study, researchers developed microparticle-embedded gas-propelled microneedles that showed higher drug loading and transdermal delivery efficiency compared to traditional microneedles.

This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.

Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.

This study found that capped mesoporous silica nanoparticles conjugated with antibodies selectively released a dye when exposed to finasteride, with low detection limits and stable performance even after storage.

This study observed that patients with isolated neutropenia exhibit significant differences in certain lymphocyte and monocyte subtypes compared to healthy controls, including higher neutrophil/lymphocyte MFI ratios and lower percentages of natural killer cells.

This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.

This review discusses various chromatographic methods for analyzing finasteride in biological fluids and provides no clinical findings, focusing on detection techniques for different concentration levels.

This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.

This study demonstrated the first successful isolation of inner ear exosomes from perilymph using a novel immunomagnetic technique, providing a potential diagnostic method for sensorineural hearing loss.

This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.

This study outlines a method to isolate hair follicle stem cells from mouse skin using fluorescence activated cell-sorting for use in research models, but reports no experimental findings.

This study reported that pelage hair follicle mesenchymal stem cells isolated from mice using Ficoll Density Gradient Sedimentation can be obtained in large numbers and may promote hair growth via exosome secretion.

This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.

This study reviewed the efficacy of mechanical fractionation techniques to produce tissue stromal vascular fraction (tSVF) and found that tSVF injections are particularly effective for conditions like osteoarthritis and wound healing, with centrifugation before fractionation improving isolation efficiency regardless of preparation method.

This study established a protocol using anti-steroid antibodies to differentially label epidermal cell contributors, suggesting potential applications in simplifying complex trace DNA mixtures before profiling.

This study found that preparing Finasteride micro and nanoparticles using a gas-antisolvent method reduced the particle size significantly.